Cervera, J., Levin, M., Mafe, S. (2024), Multicellular adaptation to electrophysiological perturbations analyzed by deterministic and stochastic bioelectrical models, Scientific Reports 2024, 27608 doi:10.1038/s41598-024-79087-7
PDF

Pai, V., Zhang, G., Levin, M. (2024), “Bioelectricity in Development, Regeneration, and Cancers” Cell Bio 2023: A Joint Meeting of the American Society of Cell Biology and European Molecular Biology Organization, Bioelectricity 2024, 6:1 doi: 10.1089/bioe.2024.0006
PDF

Djamgoz, M.B.A., Levin, M. (2024), Potential Shortcomings of Genomic Database: The Case of Nav1.5 Expression in Breast Cancer, Bioelectricity 2024, doi: 10.1089/bioe.2024.0033
PDF

Buckley, C.L., Lewens, T., Levin, M., Millidge, B., Tschantz, A., Watson, R.A. (2024), Natural Induction: Spontaneous Adaptive Organisation without Natural Selection, Entropy 2024, 26, 765, doi: 10.3390/e26090765
PDF

Tolchinsky, A., Ellis, G. F. R., Levin, M., Kaňková, Š., Burgdorf, J. S (2024), Disgust as a primary emotional system and its clinical relevance, Frontiers in Psychology 2024, 15:1454774 doi: 10.3389/fpsyg.2024.1454774
PDF

Zhang, T., Goldstein, A., Levin M. (2024), Classical sorting algorithms as a model of morphogenesis: Self-sorting arrays reveal unexpected competencies in a minimal model of basal intelligence, Adaptive Behavior 2024, doi: 10.1177/10597123241269740
PDF

Cervera, J., Manzanares, J. A., Levin, M., Mafe, S. (2024), Oscillatory phenomena in electrophysiological networks: The coupling between cell bioelectricity and transcription, Computers in Biology and Medicine 2024, 80 doi: 10.1016/j.compbiomed.2024.108964
PDF

Monzel, A. S., Levin, M., Picard, M.(2024), The energetics of cellular life transitions, Life Metabolism 2024, 3(3) doi:10.1093/lifemeta/load051
PDF

Kagan, B. J., Mahlis, M., Bhat, A., Bongard, J., Cole, V. M., Corlett, P., Gyngell, C., Hartung, T., Jupp, B., Levin, M., Lysaght, T., Opie, N., Razi, A., Smirnova, L., Tennant, Ian, Wade, P. T., Wang, G.,(2024), Toward a nomenclature consensus for diverse intelligent systems: Call for collaboration, The Innovation 2024, 5(9) doi:10.1016/j.xinn.2024.100658
PDF

Shreesha, L., Levin, M. (2024), Stress Sharing as Cognitive Glue for Collective Intelligences: a computational model of stress as a coordinator for morphogenesis, Biochemical and Biophysical Reasearch Communications, 731 2024, doi:10.1016/j.bbrc.2024.150396
PDF

Hartl, B., Risi, S., Levin, M. (2024), Evolutionary Implications of Self-Assembling Cybernetic Materials with Collective Problem-Solving Intelligence at Multiple Scales, Entropy 2024, 26(7), 532; doi:10.3390/e26070532
PDF

Yang, B., Nasab, A. M., Woodman, S.J., Thomas, E., Tilton, L.G., Levin, M., Kramer-Bottiglio, R. (2024), Self-Amputating and Interfusing Machines, Advanced Materials 2024, 2400241; doi:10.1002/adma.202400241
PDF

Levin, M.(2024), Self-Improvising Memory: A Perspective on Memories as Agential, Dynamically Reinterpreting Cognitive Glue, Entropy 2024, 26(6), 481; doi:10.3390/e26060481
PDF

Asefifeyzabadi, N., Nguyen, T., Li, H., Zhu, K., Yang , H., Baniya, P., PhD, Lopez, A. M., Gallegos, A., Hsieh, H. Dechiraju, H., Hernandez, C., Schorger, K., Recendez, C., Tebyani, M., Selberg, J., Luo, L., Muzzy, E., Hsieh, C., Barbee, A., Orozco, J., Alhamo, M.A., Levin, M., Aslankoohi, E., Gomez, M., Zhao, M., Teodorescu, M., Isseroff, R. R., Rolandi, M. (2024), A pro-reparative bioelectronic device for controlled delivery of ions and biomolecules, Wound Rep Reg 2024, 1-11 doi:10.1111/wrr.13191
PDF

McMillen, P., Levin, M. (2024), Collective intelligence: A unifying concept for integrating biology across scales and substrates, Communications Biology 7, 378 (2024). doi:10.1038/s42003-024-06037-4
PDF

Noble, P. A., Pozhitkov, A., Singh, K., Woods, E., Liu, C., Levin, M., Javan, G., Wan, J., Abouhashem, A. S., Mathew-Steiner, S. S., Sen, C. K. (2024), Unraveling the Enigma of Organismal Death: Insights, Implications, and Unexplored Frontiers, ACS Physiology, 2024 doi:10.1152/physiol.00004.2024
PDF

Fields, C., and Levin, M. (2024), Snakes and ladders in the evolution of language, Physics of Life Reviews, 2024 doi:10.1016/j.plrev.2024.04.007
PDF

Pio-Lopez, L., Levin, M. (2024), Aging as a loss of morphostatic information: a developmental bioelectricity perspective, Ageing Research Reviews, 2024, 97:102310
PDF

Balasubramanian, S., Weston, D., Levin, M., Davidian, D. C. C. (2024), Electroceuticals: emerging applications beyond the nervous system and excitable tissues, Trends Pharmacol Sci, 2024, 2109
PDF

Li, H., Yang, H.-Y., Asefifeyzabadi, N., Baniya, P., Medina Lopez, A., Gallegos, A., Zhu, K., Hsieh, H.-C., Nguyen, T., Hernandez, C., Zlobina, K., Recendez, C., Tebyani, M., Carrión, H., Selberg, J., Luo, L., Alhamo, M. A., Soulika, A. M., Levin, M., Norouzi, N., Gomez, M., Zhao, M., Teodorescu, M., Isseroff, R. R., Rolandi, M. (2024), Programmable delivery of fluoxetine via wearable bioelectronics for wound healing in vivo, Advanced Materials Technologies, 2024, 9(7) 2301115
PDF

Balasubramanian, S., Weston, D., Levin, M., Davidian, D. C. C. (2024), Charging Ahead: Examining the future therapeutic potential of electroceuticals, Advanced Therapeutics, 2024, 23003344 doi:10.1002/adtp.202300344
PDF

Fields, C., Glazebrook, J. F., and Levin, M. (2024), Principled Limitations on Self-Representation for Generic Physical Systems, Entropy, 26(3): 194
PDF

Etcheverry, M., Moulin-Frier, C., Oudeyer, P.-Y, and Levin, M. (2024), AI-driven Automated Discovery Tools Reveal Diverse Behavioral Competencies of Biological Networks, eLife, 13: RP92683
PDF

Tung, A., Sperry, M., Clawson, W., Pavuluri, A., Bulatao, S., Yue, M., Flores, R. M., Pai, V. McMillen, P., Kuchling, F., and Levin, M. (2024), Embryos assist morphogenesis of others through calcium and ATP signaling mechanisms in collective teratogen resistance, Nature Communications, 15(1): 535
PDF

O’Brien, T., Stremmel, J., Pio-Lopez, L., McMillen, P., Rasmussen-Ivey, C., and Levin, M. (2024), Machine Learning for Hypothesis Generation in Biology and Medicine: Exploring the latent space of neuroscience and developmental bioelectricity, Digital Discovery, 3(2): 249-263
PDF

McMillen, P., and Levin, M. (2024), Optical Estimation of Bioelectric Patterns in Living Embryos, in M. Bizzarri (ed.), Systems Biology: Methods in Molecular Biology, 2745: 91-102, doi:10.1007/978-1-0716-3577-3_6
PDF

Seifert, G., Sealander, A., Marzen, S., and Levin, M. (2024), From reinforcement learning to agency: Frameworks for understanding basal cognition, BioSystems, 235(1): 105107
PDF

2023

Ciaunica, A., Levin, M., Rosas, F. E., and Friston, K. (2023), Nested Selves: Self-Organization and Shared Markov Blankets in Prenatal Development in Humans, Topics in Cognitive Science, in press, doi:10.1111/tops.12717
PDF

Gumuskaya, G., Srivastava, P., Cooper, B. G., Lesser, H., Semegran, B., Garnier, S., and Levin, M. (2023), Motile Living Biobots Self-Construct from Adult Human Somatic Progenitor Seed Cells, Advanced Science, doi:10.1002/advs.202303575
PDF

Manicka, S., Pai, V. P, and Levin, M. (2023), Information integration during bioelectric regulation of morphogenesis of the embryonic frog brain, iScience, 26(12): 108398
PDF

Rouleau, N., and Levin, M. (2023), The Multiple Realizability of Sentience in Living Systems and Beyond, eNeuro, 10(11), doi:10.1523/eneuro.0375-23.2023
PDF

Blattner, M., and Levin, M. (2023) Long Range Communication via Gap Junctions and Stress in Planarian Morphogenesis: A Computational Study, Bioelectricity, 5(3): 196-209
PDF

Mathews, J., and Levin, M. (2023) Cancer’s unique bioelectric properties: from cells to body-wide networks, Comment on: “The distinguishing electrical properties of cancer cells” by Elisabetta Di Gregorio, Simone Israel, Michael Staelens, Gabriella Tankel, Karthik Shankar, and Jack A. Tuszynski, Physics of Life Reviews, 47: 113-115
PDF

Dungan, J., Mathews, J., Levin, M., and Koomson, V. (2023), Optimization of Oligomer Stamping Technique for Normally Closed Elastomeric Valves on Glass Substrate, Micromachines, 14(9): 1659
PDF

Levin, M. (2023), Collective Intelligence of Morphogenesis as a Teleonomic Process, in Corning, P. A., Kauffman, S. A., Noble, D., Shapiro, J. A., Vane-Wright, R. I. Pross, A. (Eds.), Evolution "On Purpose": Teleonomy in Living Systems, The MIT Press: Cambridge, MA, 175-197
PDF

Clawson, W. P., and Levin, M. (2023), Endless forms most beautiful 2.0: teleonomy and the bioengineering of chimaeric and synthetic organisms, Biological Journal of the Linnean Society, 139(4): 457-486
PDF

Grodstein, J., McMillen, P., and Levin, M. (2023), Closing the Loop on Morphogenesis: A Mathematical Model of Morphogenesis by Closed-Loop Reaction-Diffusion, Frontiers in Cell and Developmental Biology, 11: 1087650
PDF

Cervera, J., Levin, M., and Mafé, S. (2023), Correcting instructive electric potential patterns in multicellular systems: External actions and endogenous processes, Biochimica et Biophysica Acta (BBA) - General Subjects, 1867(10): 130440
PDF

Welch, P., Grasso, C., Gumuskaya, G., Levin, M., and Bongard, J. (2023), Searching in the Dark: Evolving Biobot Swarm Compositions to Efficiently Explore Obstructed Environments, Proceedings of ALIFE 2023: Ghost in the Machine, article 70, doi:10.1162/isal_a_00683
PDF

Lagasse, E., and Levin, M. (2023), Future Medicine: from molecular pathways to the collective intelligence of the body, Trends in Molecular Medicine, 29(9): 687-710
PDF

Rouleau, N., and Levin, M. (2023), Multiple ways to implement and infer sentience: Commentary on Segundo-Ortiz & Calvo on Plant Sentience, Animal Sentience, 8(33): 30
PDF

Masuelli, S., Real, S., McMillen, P., Oudin, M., Levin, M., and Roqué, M. (2023), The Yin and Yang of Breast Cancer: Ion Channels as Determinants of Left-Right Functional Differences, International Journal of Molecular Sciences, 24(13): 11121
PDF

Witkowski, O., Doctor, T., Solomonova, E., Duane, B., and Levin, M. (2023), Towards an Ethics of Autopoietic Technology: Stress, Care, and Intelligence, Biosystems, 231: 104964
PDF

Cervera, J., Levin, M., and Mafé, S. (2023), Bioelectricidad en agregados multicelulares de células no excitables: modelos biofísicos, Revista Española de Física, 37(2): 24-29

Ciaunica, A., Shmeleva, E. V., and Levin, M. (2023), The Brain is not Mental! Coupling Neuronal and Immune Cellular Processing in Human Organisms, Frontiers in Integrative Neuroscience, 17: 1057622
PDF

Fields, C., and Levin, M. (2023), Regulative development as a model for origin of life and artificial life studies, Biosystems, 229: 104927
PDF

Watson, R., and Levin, M. (2023), The collective intelligence of evolution and development, Collective Intelligence, 2(2), doi:10.1177/26339137231168355
PDF

Levin, M. (2023), Bioelectric networks: the cognitive glue enabling evolutionary scaling from physiology to mind, Animal Cognition, doi:10.1007/s10071-023-01780-3
PDF

Fields, C., Fabrocini, F., Friston, K., Glazebrook, J. F., Hazan, H., Levin, M., and Marcianò, A. (2023), Control flow in active inference systems Part II: Tensor networks as general models of control flow, IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, doi:10.1109/TMBMC.2023.3272158
PDF

Fields, C., Fabrocini, F., Friston, K., Glazebrook, J. F., Hazan, H., Levin, M., and Marcianò, A. (2023), Control flow in active inference systems Part I: Classical and quantum formulations of active inference, IEEE Transactions on Molecular, Biological, and Multi-Scale Communications, doi:10.1109/TMBMC.2023.3272150
PDF

Levin, M. (2023), Darwin’s agential materials: evolutionary implications of multiscale competency in developmental biology, Cellular and Molecular Life Sciences, 80: 142
PDF

Pio-Lopez, L., and Levin, M. (2023), Morphoceuticals: Perspectives for discovery of drugs targeting anatomical control mechanisms in regenerative medicine, cancer and aging, Drug Discovery Today, 28(6): 103585
PDF

Mathews, J., Chang, J., Devlin, L., and Levin, M. (2023), Cellular Signaling Pathways as Plastic, Proto-cognitive Systems: Implications for Biomedicine, Patterns, 4: 100737
PDF

Blackiston, D., Kriegman, S., Bongard, J., and Levin, M. (2023), Biological Robots: Perspectives on an Emerging Interdisciplinary Field, Soft Robotics, 10(4): 694-686
PDF

Pio-Lopez, L., Bischof, J., LaPalme, J. V., and Levin, M. (2023), The scaling of goals via homeostasis: an evolutionary simulation, experiment and analysis, Interface Focus, 13(3): 20220072
PDF

Manicka, S., Johnson, K., Levin, M., and Murrugarra, D. (2023), The nonlinearity of regulation in biological networks, npj Systems Biology and Applications, 9(1): 10
PDF

Bongard, J., and Levin, M. (2023), There’s Plenty of Room Right Here: Biological Systems as Evolved, Overloaded, Multi-Scale Machines, Biomimetics, 8(1): 110
PDF

Davies, J., and Levin, M. (2023), Synthetic morphology with agential materials, Nature Reviews Bioengineering, 1(1): 46-59
PDF

Shreesha, L., and Levin, M. (2023), Cellular Competency during Development Alters Evolutionary Dynamics in an Artificial Embryogeny Model, Entropy, 25(1): 131
PDF

Cervera, J., Levin, M., and Mafe, S. (2023), Bioelectricity of non-excitable cells and multicellular pattern memories: Biophysical modeling, Physics Reports, 1004: 1-31, doi:10.1016/j.physrep.2022.12.003
PDF

Biswas, S., Clawson, W., and Levin. M. (2023), Learning in Transcriptional Network Models: Computational Discovery of Pathway-level Memory and Effective Interventions, International Journal of Molecular Sciences, 24(1): 285
PDF

Cervera, J., Manzanares, J. A., Levin, M., and Mafe, S. (2023), Transplantation of fragments from different planaria: a bioelectrical model for head regeneration, Journal of Theoretical Biology, 558: 111356
PDF

2022

< Back to Years

Hazan, H., and Levin, M. (2022), Exploring the Behavior of Bioelectric Circuits Using Evolution Heuristic Search, Bioelectricity, 4(4): 207-227
PDF

Dechiraju, H., Selberg, J., Jia, M., Pansodtee, P., Li, H., Hsieh, H-C., Hernandez, C., Asefifeyzabadi, N., Nguyen, T., Baniya, P., Marquez, G., Rasmussen-Ivey, C., Bradley, C., Teodorescu, M., Gomez, M., Levin, M., and Rolandi, M. (2022), On-chip on-demand delivery of K+ for in vitro bioelectronics, AIP Advances, 12(12): 125205
PDF

Pio-Lopez, L., Kuchling, F., Tung, A., Pezzulo, G., and Levin, M. (2022), Active Inference, Morphogenesis, and Computational Psychiatry, Frontiers in Computational Neuroscience, 16: 988977
PDF

Fields, C., Friston, K., Glazebrook, J. F., Levin, M., and Marcianò, A. (2022), The Free Energy Principle induces neuromorphic development, Neuromorphic Computing and Engineering, 2: 042002
PDF

McMillen, P., and Levin, M. (2022), Information Theory as an experimental tool for integrating disparate biophysical signaling modules, International Journal of Molecular Sciences, 23(17): 9580
PDF

Cavuoti, L., Sacco, F., Randazzo, E., & Levin, M. (2022), Adversarial Takeover of Neural Cellular Automata, Proceedings of the 2022 Conference on Artificial Life (ALIFE 2022), p. 256-263
PDF

Smiley, P., and Levin, M. (2022), Competition for Finite Resources as Coordination Mechanism for Morphogenesis: an evolutionary algorithm study of digital embryogeny, BioSystems, 221: 104672
PDF

Pai, V. P., Cooper, B. G., and Levin, M. (2022), Screening Biophysical Sensors and Neurite Outgrowth Actuators in Human Induced-Pluripotent-Stem-Cell-Derived Neurons, Cells, 11(16): 2470
PDF

Levin, M. (2022), Generalizing frameworks for sentience beyond natural species, Animal Sentience, 7(32): 15
PDF

Sperry, M. M., Novak, R., Keshari, V., Dinis, A. L. M., Cartwright, M. J., Camacho, D. M., Paré, J. F., Super, M., Levin, M., and Ingber, D. E. (2022), Enhancers of Host Immune Tolerance to Bacterial Infection Discovered Using Linked Computational and Experimental Approaches, Advanced Science, 9(26): 2200222 [cover]
PDF

Pai, V. P., and Levin, M. (2022), HCN2 Channel-induced Rescue of Brain, Eye, Heart, and Gut Teratogenesis Caused by Nicotine, Ethanol, and Aberrant Notch Signaling, Wound Repair and Regeneration, 30(6): 681-706
PDF

Doctor, T., Witkowski, O., Solomonova, E., Duane, B., and Levin, M. (2022), Biology, Buddhism, and AI: Care as the Driver of Intelligence, Entropy, 24(5): e24050710
PDF

Fields, C., and Levin, M. (2022), Competency in Navigating Arbitrary Spaces as an Invariant for Analyzing Cognition in Diverse Embodiments, Entropy, 24(6): 819
PDF

Fields, C., Glazebrook, J. F., and Levin, M. (2022), Neurons as hierarchies of quantum reference frames, Biosystems, 219: 104714
PDF

Fields, C., Friston, K., Glazebrook, J. F., and Levin, M. (2022), A free energy principle for generic quantum systems, Progress in Biophysics and Molecular Biology, 173: 36-59
PDF

Kuchling, F., Fields, C., and Levin, M. (2022) Metacognition as a Consequence of Competing Evolutionary Time Scales, Entropy, 24(5): 601
PDF

Watson, R. A., Levin, M., and Buckley, C. L. (2022) Design for an Individual: Connectionist approaches to the evolutionary transitions in individuality, Frontiers in Ecology and Evolution, 10: 823588
PDF

Levin, M. (2022), Technological Approach to Mind Everywhere: an experimentally-grounded framework for understanding diverse bodies and minds, Frontiers in Systems Neuroscience, 16: 768201
PDF

Kudithipudi, D., Aguilar-Simon, M., Babb, J., Bazhenov, M., Blackiston, D., Bongard, J., Brna, A. P., Raja, S. C., Cheney, N., Clune, J., Daram, A., Fusi, S., Helfer, P., Kay, L., Ketz, N., Kira, Z., Kolouri, S., Krichmar, J. L., Kriegman, S., Levin, M., Madireddy, S., Manicka, S., Marjaninejad, A., McNaughton, B., Miikkulainen, R., Navratilova, Z., Pandit, T., Parker, A., Pilly, P. K., Risi, S., Sejnowski, T. J., Soltoggio, A., Soures, N., Tolias, A. S., Urbina-Meléndez, D., Valero-Cuevas, F. J., van de Ven, G. M., Vogelstein, J. T., Wang, F., Weiss, R., Yanguas-Gil, A., Zou, X., and Siegelmann, H. (2022), Biological underpinnings for lifelong learning machines, Nature Machine Intelligence, 4(3): 196-210
PDF

Sperry, M. M., Murugan, N. J., and Levin, M. (2022), Studying Protista WBR and Repair Using Physarum polycephalum, in S. Blanchoud and B. Galliot (eds.), Whole-Body Regeneration: Methods in Molecular Biology, 2450: 51-67
PDF

Mathews, J., Kuchling, F., Baez-Nieto, D., Diberardinis, M., Pan, J. Q., and Levin, M. (2022), Ion Channel Drugs Suppress Cancer Phenotype in NG108-15 and U87 Cells: Toward Novel Electroceuticals for Glioblastoma, Cancers 14(6): 1499
PDF

Levin, M., and Yuste, R. (2022), Modular cognition, Aeon Essays [cover]
PDF

Nanos, V., and Levin, M. (2022), Multi-scale Chimerism: an experimental window on the algorithms of anatomical control, Cells and Development, 169: 203764 [cover]
PDF

Grodstein, J., and Levin, M. (2022), A Computational Approach to Explaining Bioelectrically-induced Persistent, Stochastic Changes of Axial Polarity in Planarian Regeneration, Bioelectricity, 4(1): 18-30
PDF

Adelfio, M., Bonzanni, M., Levin, M., and Kaplan, D. L. (2022), Impact of Membrane Voltage on Formation and Stability of Human Renal Tubules in Vitro, ACS Biomaterials Science & Engineering, 8(3): 1239-1246
PDF

Masuelli, S., Sebastian, R., Campoy, E., Branham, M. T., Marzese, D. M., Matthew, S., DeBlas, G., Rodolfo, A., Levin, M., and Roque, M. (2022), When left does not seem right: epigenetic and bioelectric differences between left- and right-sided breast cancer, Molecular Medicine, 28(1): 15
PDF

Murugan, N. J., Vigran, H. J., Miller, K., Golding, A., Pham, Q. L., Sperry, M., Rasmussen-Ivey, C., Kane, A. W., Kaplan, D. L., and Levin, M. (2022), Acute multidrug delivery via a wearable bioreactor facilitates long-term limb regeneration and functional recovery in adult Xenopus laevis, Science Advances, 8(4): abj2164 [cover]
PDF

Manicka, S., and Levin, M. (2022), Minimal developmental computation: a causal network approach to understand morphogenetic pattern formation, Entropy, 24: 107
PDF

Payne, S. L., Ram, P., Srinivasan, D. H., Le, T. T., Levin, M., and Oudin, M. J. (2022), Potassium channel-driven bioelectric signalling regulates metastasis in triple-negative breast cancer, EBioMedicine, 75: 103767
PDF

2021

< Back to Years

Klein, B., Hoel, E., Swain, A., Griebenow, R., and Levin, M. (2021), Evolution and emergence: higher order information structure in protein interactomes across the tree of life, Integrative Biology, 13(12): 283-294 [cover]
PDF

Yuste, R., and Levin, M. (2021), New Clues about the Origins of Biological Intelligence, Scientific American, December 2021
PDF

Kriegman, S., Blackiston, D., Levin, M., and Bongard, J. (2021), Kinematic self-replication in reconfigurable organisms, Proceedings of the National Academy of Science, 118(49): e2112672118
PDF

Abramson, C., and Levin, M. (2021), Behaviorist Approaches to Investigating Memory and Learning: A Primer for Synthetic Biology and Bioengineering, Communicative & Integrative Biology, 14(1): 230-247
PDF

Minh-Thai, T. N., Samarasinghe, S., and Levin, M. (2021), A Comprehensive Conceptual and Computational Dynamics Framework for Autonomous Regeneration Systems, Artificial Life, 27(2): 80-104
PDF

Riol, A., Cervera, J., Levin, M., and Mafe, S. (2021), Cell Systems Bioelectricity: How Different Intercellular Gap Junctions Could Regionalize a Multicellular Aggregate, Cancers, 13(21): 5300
PDF

Grodstein, J., and Levin, M. (2021), Stability and robustness properties of bioelectric networks: A computational approach, Biophysics Review, 2: 031305
PDF

Guidetti, G., Levy, G., Matzeu, G., Finkelstein, J. M., Levin, M., and Omenetto, F. G. (2021), Unmixing octopus camouflage by multispectral mapping of Octopus bimaculoides' chromatic elements, Nanophotonics, 10(9): 2441-2450
PDF

McMillen, P., Oudin, M. J, Levin, M., and Payne, S. L. (2021), Beyond Neurons: Long Distance Communication in Development and Cancer, Frontiers in Cell and Developmental Biology, 9: 739024
PDF

Levin, M. (2021), Bioelectrical approaches to cancer as a problem of the scaling of the cellular self, Progress in Biophysics and Molecular Biology, 165: 102-113
PDF

Kriegman, S., Nasab, A-M., Blackiston, D., Steele, H., Levin, M., Kramer-Bottiglio, R., and Bongard, J. (2021), Scale invariant robot behavior with fractals, Robotics: Science and Systems (RSS 2021), doi:10.15607/RSS.2021.XVII.059
PDF

Cervera, J., Levin, M., and Mafe, S. (2021), Morphology changes induced by intercellular gap junction blocking: a reaction-diffusion mechanism, BioSystems, 209: 104511
PDF

Fields, C., and Levin, M. (2021), Metabolic limits on classical information processing by biological cells, BioSystems, 209: 104513
PDF

Davidian, D., and Levin, M. (2021), Inducing Vertebrate Limb Regeneration: A Review of Past Advances and Future Outlook, Cold Spring Harbor Perspectives in Biology, doi:10.1101/cshperspect.a040782
PDF

Fields, C., Glazebrook, J. F., and Levin, M. (2021), Minimal physicalism as a scale-free substrate for cognition and consciousness, Neuroscience of Consciousness, 2021(2): niab013
PDF

Murugan, N., Kaltman, D., Jin, H., Chien, M., Flores, R., Nguyen, C., Tuzoff, D., Minabutdinov, A., Kane, A., Novak, R., Ingber, D., and Levin, M. (2021), Mechanosensation Mediates Long-Range Spatial Decision-Making in an Aneural Organism, Advanced Materials, 33(34): 2008161 [cover]
PDF

Niklasson, E., Mordvintsev, A., Randazzo, E., and Levin, M. (2021), Self-organising Textures: Neural Cellular Automata Model of Pattern Formation, Distill, 6(2), doi:10.23915/distill.00027.003
PDF

Levin, M. (2021), Life, death, and self: Fundamental questions of primitive cognition viewed through the lens of body plasticity and synthetic organisms, Biochemical and Biophysical Research Communications, 564: 114-133 [cover]
PDF

Randazzo, E., Mordvintsev, A., Niklasson, E., and Levin, M. (2021), Adversarial Reprogramming of Neural Cellular Automata: a robustness investigation, Distill, 6(5), doi:10.23915/distill.00027.004
PDF

Ebrahimkhani, M., and Levin, M. (2021), Synthetic living machines: A new window on life, iScience, 24(5): 102505
PDF

Blackiston, D., Lederer, E., Kriegman, S., Garnier, S., Bongard, J., and Levin, M. (2021), A cellular platform for the development of synthetic living machines, Science Robotics, 6(52): eabf1571
PDF

Levin, M. (2021), Unlimited plasticity of embodied, cognitive subjects: a new playground for the UAL framework, Biology and Philosophy, 36(2): 17
PDF

Rouleau, N., Cairns, D. M., Rusk, W., Levin, M., and Kaplan, D. (2021), Learning and synaptic plasticity in 3D bioengineered neural tissues Neuroscience Letters, 750: 135799
PDF

Levin, M. (2021), Bioelectric Signaling: Reprogrammable Circuits Underlying Embryogenesis, Regeneration, and Cancer, Cell, 184(8): 1971-1989
PDF

Bongard, J., and Levin, M. (2021), Living things are not (20th Century) machines: updating mechanism metaphors in light of the modern science of machine behavior, Frontiers in Ecology and Evolution, 9: 650726
PDF

Levin, M., Keijzer, F., Lyon, P., and Arend, D. (2021), Uncovering cognitive similarities and differences, conservation and innovation, Philosophical Transactions of the Royal Society B, 376(1821): 20200458 [cover]
PDF

Lyon, P., Keijzer, F., Arendt, D., and Levin, M. (2021), Reframing cognition: getting down to biological basics, Philosophical Transactions of the Royal Society B, 376(1820): 20190750 [cover]
PDF

Shah, D., Yang, B., Kriegman, S., Levin, M., Bongard, J., and Kramer-Bottiglio, R. (2021), Shape changing robots: bioinspiration, simulation, and physical realization, Advanced Materials, 33(19): 2170150
PDF

Srivastava, P., Kane, A., Harrison, C., and Levin, M. (2021), A Meta-Analysis of Bioelectric Data in Cancer, Embryogenesis, and Regeneration, Bioelectricity, 3(1): 42-67
PDF

Pezzulo, G., Lapalme, J., Durant, F., and Levin, M. (2021), Bistability of Somatic Pattern Memories: Stochastic Outcomes in Bioelectric Circuits Underlying Regeneration, Philosophical Proceedings of the Royal Society B, 376(1821): 20190765
PDF

Biswas, S., Manicka, S., Hoel, E., and Levin, M. (2021), Gene Regulatory Networks Exhibit Several Kinds of Memory: Quantification of Memory in Biological and Random Transcriptional Networks, iScience, 24(3): 102131
PDF

Nanos, V., and Levin, M. (2021), Rewiring Endogenous Bioelectric Circuits in the Xenopus laevis Embryo Model, in M. R. Ebrahimkhani and J. Hislop (Eds.), Programmed Morphogenesis: Methods in Molecular Biology, 2258: 93-103
PDF

Pentagna, N., Pinheiro da Costa, T., Soares Dos Santos, F., Martins de Almeida, F., Martinez, A. M. B., Abreu, J. G., Levin, M., and Carneiro, K. (2021), Epigenetic control of myeloid cells behavior by Histone Deacetylase Activity (HDAC) during tissue and organ regeneration in Xenopus laevis, Developmental and Comparative Immunology, 114: 103840
PDF

2020

< Back to Years

Randazzo, E., Mordvintsev, A., Niklasson, E., Levin, M., and Greydanus, S. (2020), Self-classifying MNIST Digits Achieving Distributed Coordination with Neural Cellular Automata, Distill, 5(8), doi:10.23915/distill.00027.002
PDF

Mordvintsev, A., Randazzo, E., Niklasson, E., and Levin, M. (2020), Growing Neural Cellular Automata: Differentiable Model of Morphogenesis, Distill, 5(2), doi:10.23915/distill.00027.002
PDF

Cervera, J., Ramirez, P., Levin, M., and Mafe, S. (2020), Community effects allow bioelectrical reprogramming of cell membrane potentials in multicellular aggregates: Model simulations, Physical Review E, 102(5): 052412
PDF

Fields, C., and Levin, M. (2020), How Do Living Systems Create Meaning?, Philosophies, 5(4): 36
PDF

Selberg, J., Jafari, M., Mathews, J., Jia, M., Pansodtee, P., Dechiraju, H., Wu, C., Cordero, S., Flora, A., Yonas, N., Jannetty, S., Diberardinis, M., Teodorescu, M., Levin, M., Gomez, M., and Rolandi, M. (2020), Machine Learning-Driven Bioelectronics for Closed-Loop Control of Cells, Advanced Intelligent Systems, 2(12): 2000140 [cover]
PDF

Sousounis, K., Erdogan, B., Levin, M., and Whited, J. L. (2020), Precise control of ion channel and gap junction expression is required for patterning of the regenerating axolotl limb, International Journal of Developmental Biology, 64(10-11-12): 485-494
PDF

Fields, C., and Levin, M. (2020), Why isn't sex optional? Stem-cell competition, loss of regenerative capacity, and cancer in metazoan evolution, Communicative & Integrative Biology, 13(1): 170-183
PDF

Levin, M., and Dennett, D. C. (2020), How to understand cells, tissues and organisms as agents with agendas, Aeon Essays
PDF

Fields, C., and Levin, M. (2020), Does evolution have a target morphology?, Organisms. Journal of Biological Sciences, 4(1): 57-76
PDF

Erndt-Marino, J., Yeisley, D. J., Chen, H., Levin, M., Kaplan, D. L., and Hahn, M. S. (2020), Interferon-Gamma Stimulated Murine Macrophages In Vitro: Impact of Ionic Composition and Osmolarity and Therapeutic Implications, Bioelectricity, 2(1): 48-58
PDF

Jia, M., Dechiruji, H., Selberg J., Pansodtee P., Mathews, J., Wu, C., Levin, M., Teodorescu, M., and Rolandi, M. (2020), Bioelectronic Control of Chloride Ions and Concentration with Ag/AgCl Contacts, APL Materials, 8(9): 091106
PDF

Levin, M. (2020), How Groups of Cells Cooperate to Build Organs and Organisms, The Scientist, 34(9): 38-45 [cover]
PDF

Bischof, J., Day, M., Miller, K., LaPalme, J., and Levin, M. (2020), Nervous System and Tissue Polarity Dynamically Adapt to New Morphologies in Planaria, Developmental Biology, 467 (1-2): 51-65 [cover]
PDF

Kuchling, F., Friston, K., Georgiev, G., and Levin, M. (2020), Integrating Variational Approaches to Pattern Formation into a Deeper Physics: Reply to comments on "Morphogenesis as Bayesian Inference: A Variational Approach to Pattern Formation and Manipulation in Complex Biological Systems", Physics of Life Reviews, 33: 125-128
PDF

Leronni, A., Bardella, L., Dorfmann, L., Pietak, A., and Levin, M. (2020), On the coupling of mechanics with bioelectricity and its role in morphogenesis, Journal of the Royal Society Interface, 17(167): 20200177
PDF

Levin, M., and Rajnicek, A. M. (2020), Richard Borgens, 1946-2019, Bioelectricity, 2(2): 205
PDF

Hoel, E., and Levin, M. (2020), Emergence of Informative Higher Scales in Biological Systems: a computational toolkit for optimal prediction and control, Communicative & Integrative Biology, 13(1): 108-118
PDF

Rouleau, N., Bonzanni, M., Erndt-Marino, J., Sievert, K., Ramirez, C., Rusk, W., Levin, M., and Kaplan, D. (2020), A 3D tissue model of traumatic brain injury with excitotoxicity that is inhibited by chronic exposure to gabapentinoids, Biomolecules, 10(8): 1196
PDF

Levin, M., Bongard, J., and Lunshof, J. E. (2020), Applications and ethics of computer-designed organisms, Nature Reviews Molecular Cell Biology, 21(11): 655-656
PDF

Levin, M. (2020), Opinion: Use the Pandemic to Expand the Lab to the Home, The Scientist
PDF

Williams, K., Bischof, J., Lee, F., Miller, K., LaPalme, J., Wolfe, B., and Levin, M. (2020), Regulation of axial and head patterning during planarian regeneration by a commensal bacterium, Mechanisms of Development, 163: 103614 [cover]
PDF

Gawne, R., McKenna, K., and Levin, M. (2020), Competitive and Coordinative Interactions between Body Parts Produce Adaptive Developmental Outcomes, BioEssays, 42(8): 1900245 [cover]
PDF

Fields, C., and Levin, M. (2020), Scale-Free Biology: Integrating Evolutionary and Developmental Thinking, BioEssays, 42(8): 1900228 [cover]
PDF

Pai, V., Cervera, J., Mafe, S., Willocq, V., Lederer, E., and Levin, M. (2020), HCN2 Channel-induced Rescue of Brain Teratogenesis via local and long-range bioelectric repair, Frontiers in Cellular Neuroscience, 14: 136
PDF

Cervera, J., Levin, M., and Mafe, S. (2020), Bioelectrical Coupling of Single-Cell States in Multicellular Systems, Journal of Physical Chemistry Letters, 11(9): 3234-3241
PDF

Leigh, N. D., Sessa, S., Dragalzew, A. C., Payzin-Dogru, D., Sousa, J. F., Aggouras, A. N., Johnson, K., Dunlap, G. S., Haas, B. J., Levin, M., Schneider, I., and Whited, J. L. (2020), von Willebrand factor D and EGF domains is an evolutionarily conserved and required feature of blastemas capable of multitissue appendage regeneration, Evolution & Development, 22(4): 297-311 [cover]
PDF

Kuchling, F., Friston, K., Georgiev, G., and Levin, M. (2020), Morphogenesis as Bayesian Inference: a Variational Approach to Pattern Formation and Control in Complex Biological Systems, Physics of Life Reviews, 33: 88-108
PDF

Jajoo, A., Donlon, C., Shnayder, S., Levin, M., and McVey, M. (2020), Sertraline induces DNA damage and cellular toxicity in Drosophila that can be ameliorated by antioxidants, Scientific Reports, 10: 4512
PDF

Levin, M. (2020), Revisiting Burr and Northrop's 'The Electro-Dynamic Theory of Life', Biological Theory, 15: rr83-90
PDF

Sousounis, K., Bryant, D. M., Fernandez, J. M., Eddy, S. S., Tsai, S. L., Gundberg, G. C., Han, J., Courtemanche, K., Levin, M., and Whited, J. L. (2020), Eya2 promotes cell cycle progression by regulating DNA damage response during vertebrate limb regeneration, eLIFE, 9: e51217
PDF

Kriegman, S., Nasab, A. M., Shah, D., Steele, H., Branin, G., Levin, M., Bongard, J. and Kramer-Bottiglio, R. (2020), Scalable sim-to-real transfer of soft robot designs, Proceedings of the 3rd IEEE International Conference on Soft Robotics (RoboSoft 2020), p. 359-366
PDF

Fields, C., and Levin, M. (2020), Does regeneration recapitulate phylogeny? Communicative & Integrative Biology, 13(1): 27-38
PDF

Herrera-Rincon, C., Paré, J-F., Martyniuk, C. J., Jannetty, S. K., Harrison C., Fischer, A., Dinis, A., Keshari, V., Novak, R., and Levin, M. (2020), An in vivo brain-bacteria interface: the developing brain as a key regulator of innate immunity, npj Regenerative Medicine, 5:2
PDF

McMillen, P., Novak, R., and Levin, M. (2020), Toward Decoding Bioelectric Events in Xenopus Embryogenesis: New Methodology for Tracking Interplay Between Calcium and Resting Potentials In Vivo, Journal of Molecular Biology, 432(2): 605-620 [cover]
PDF

Davison, A., McDowell, G. S., Holden, J. M., Johnson, H. F., Wade, C. M., Chiba, S., Jackson, D. J., Levin, M., and Blaxter, M. L. (2020), Formin, an opinion, Development, 147: dev187427
PDF

Bonzanni, M., Rouleau, N., Levin, M., and Kaplan, D. L. (2020), Optogenetically induced cellular habituation in non-neuronal cells, PLOS One, 15(1): e0227230
PDF

Tung, A., and Levin, M. (2020), Extra-genomic instructive influences in morphogenesis: A review of external signals that regulate growth and form, Developmental Biology, 461(1): 1-12 [cover]
PDF

Kriegman, S., Blackiston, D., Levin, M., and Bongard, J. (2020), A scalable pipeline for designing reconfigurable organisms, Proceedings of the National Academy of Sciences of the United States, 432(2): 605-620
PDF

Kamaldinov, T., Erndt-Marino, J., Levin, M., Kaplan, D. L., and Hahn, M. S. (2020), Assessment of Enrichment of Human Mesenchymal Stem Cells Based on Plasma and Mitochondrial Membrane Potentials, Bioelectricity, 2(1): 21-32
PDF

Healy, D., Faber, C., Lapalme, J., and Levin, M. (2020), Post-SSRI Sexual Dysfunction: a bioelectric mechanism?, Bioelectricity, 2(1): 7-13
PDF

Levin, M. (2020), The Biophysics of Regenerative Repair Suggests New Perspectives on Biological Causation, BioEssays, 42(2): 1900146
PDF

Cervera, J., Meseguer, S., Levin, M., and Mafe, S. (2020), Bioelectrical model of head-tail patterning based on cell ion channels and intercellular gap junctions, Bioelectrochemistry, 132: 107410
PDF

Fields, C., Bischof, J., and Levin, M. (2020), Morphological Coordination: A Common Ancestral Function Unifying Neural and Non-Neural Signaling, Physiology, 35: 16-30
PDF

Bonzanni, M., Payne, S. L., Adelfio, M., Kaplan, D. L., Levin, M., and Oudin, M. J. (2020), Defined extracellular ionic solutions to study and manipulate the cellular resting membrane potential, Biology Open, 9(1): bio048553
PDF

2019

< Back to Years

Levin, M., Selberg, J., and Rolandi, M. (2019), Endogenous Bioelectrics in Development, Cancer, and Regeneration: Drugs and Bioelectronic Devices as Electroceuticals for Regenerative Medicine, iScience, 22: 519-533
PDF

Manicka, S., and Levin, M. (2019), Modeling somatic computation with non-neural bioelectric networks, Scientific Reports, 9: 18612
PDF

Levin, M. (2019), The Computational Boundary of a 'Self': Developmental Bioelectricity Drives Multicellularity and Scale-Free Cognition, Frontiers in Psychology, 10: 2688
PDF

Emmons-Bell, M., Durant, F., Tung, A., Pietak, A., Miller, K., Kane, A., Martyniuk, C. J., Davidian, D., Morokuma, J., and Levin, M. (2019), Regenerative Adaptation To Electrochemical Perturbation In Planaria: A Molecular Analysis Of Physiological Plasticity, iScience, 22: 147-165
PDF

Atsuta, Y., Tomizwa, R. R., Levin, M., and Tabin, C. J. (2019), L-type voltage-gated Ca²⁺ channel Ca_V1.2 regulates chondrogenesis during limb development, Proceedings of the National Academy of Sciences of the United States, 116(43): 21592-21601
PDF

Grasman, J., Williams, M., Razis, C., Bonzanni, M., Golding, A., Cairns, D. M., Levin, M., and Kaplan, D. L. (2019), Hyperosmolar potassium inhibits myofibroblast conversion and reduces scar tissue formation, ACS Biomaterials Science & Engineering, 5(10): 5327-5336
PDF

Levin, S., and Levin, M. (2019), Managing Ideas, People, and Projects: Organizational Tools and Strategies for Researchers, iScience, 20: 278-291
PDF

Payne, S. L., Levin, M., and Oudin, M. J. (2019), Bioelectric control of metastasis in solid tumors, Bioelectricity, 1(3): 114-130
PDF

Fields, C., and Levin, M. (2019), Somatic Multicellularity as a Satisficing Solution to the Prediction-Error Minimization Problem, Communicative & Integrative Biology, 12(1): 119-132
PDF

Punjiya, M., Nehad, H. R., Mathews, J., Levin, M., and Sonkusale, S. (2019), A flow through device for simultaneous dielectrophoretic cell trapping and AC electroporation, Scientific Reports, 9: 11988
PDF

Whited, J., and Levin, M. (2019), Bioelectrical controls of morphogenesis: from ancient mechanisms of cell coordination to biomedical opportunities, Current Opinion in Genetics & Development, 57: 61-69 [cover]
PDF

Levin, M., and Martinez-Arias, A. (2019), Reverse-engineering growth and form in Heidelberg, Development, 146(14): dev177261
PDF

Kriegman, S., Walker, S., Shah, D. S., Levin, M., Kramer-Bottiglio, R., and Bongard, J. (2019), Automated Shapeshifting for Function Recovery in Damaged Robots, Proceedings of Robotics: Science and Systems XV: 28
PDF

Cervera, C., Pai, V. P., Levin, M., and Mafe, S. (2019), From non-excitable single-cell to multicellular bioelectrical states supported by ion channels and gap junction proteins: electrical potentials as distributed controllers, Progress in Biophysics and Molecular Biology, 149: 39-53 [cover]
PDF

Bonzanni, M., Rouleau, N., Levin, M., and Kaplan, D. (2019), On the generalization of habituation: how discrete biological systems respond to repetitive stimuli, BioEssays, 41(7): 1900028
PDF

Beane, W. S., Adams, D. S., Morokuma, J., and Levin, M. (2019), Live Imaging of Intracellular pH in Planarians Using the Ratiometric Fluorescent Dye SNARF-5F-AM, Biology Methods and Protocols, 4(1): bpz005
PDF

Cervera, J., Manzanares, J. A., Mafe, S., and Levin, M. (2019), Synchronization of Bioelectric Oscillations in Networks of Nonexcitable Cells: From Single-Cell to Multicellular States, Journal of Physical Chemistry B, 123(18): 3924-3934 [cover]
PDF

Manicka, S., and Levin, M. (2019), The Cognitive Lens: a primer on conceptual tools for analysing information processing in developmental and regenerative morphogenesis, Philosophical Transactions of the Royal Society B, 374(1774): 20180369
PDF

Pietak, A., Bischof, J., LaPalme, J., Morokuma, J., and Levin, M. (2019), Neural control of body-plan axis in regenerating planaria, PLOS Computational Biology, 15(4): e1006904
PDF

Bizzari, M., Brash, D., Briscoe, J., Grieneisen, V., Stern, C. D., and Levin, M. (2019), A Call for a Better Understanding of Causation in Cell Biology, Nature Reviews Molecular Cell Biology, 20(5): 261-262
PDF

Sundelacruz, S., Moody, A. T., Levin, M., and Kaplan, D. (2019), Membrane potential depolarization alters calcium flux and phosphate signaling during osteogenic differentiation of human mesenchymal stem cells, Bioelectricity, 1(1): 56-66
PDF

Hammelman, J., Siegelmann, H., Manicka, S., and Levin, M. (2019), Toward modeling regeneration via adaptable echo state networks, in A. Adamatzky, S. Akl, and G. Sirakoulis (Eds.), From parallel to emergent computing, Chapter 6, pages 117-133, CRC Press: Boca Raton, FL

Berard, A., Levin, M., Sadler, T., and Healy, D. (2019), Selective Serotonin Reuptake Inhibitor Use During Pregnancy and Major Malformations: The Importance of Serotonin for Embryonic Development and the Effect of Serotonin Inhibition on the Occurrence of Malformations, Bioelectricity, 1(1): 18-29
PDF

Ferenc, N. N., and Levin, M. (2019), Effects of ivermectin exposure on regeneration of D. dorotocephala planaria: exploiting human-approved ion channel drugs as morphoceuticals, Macromolecular Bioscience, 19(3): 1800237 [cover]
PDF

Levin, M., Pietak, A., and Bischof, J. (2019), Planarian Regeneration as a Model of Anatomical Homeostasis: Recent Progress in Biophysical and Computational Approaches, Seminars in Cell and Developmental Biology, 87: 125-144
PDF

Durant, F., Bischof, J., Fields, C., Morokuma, J., LaPalme, J., Hoi, A., and Levin, M. (2019), The role of early bioelectric signals in the regeneration of planarian anterior/posterior polarity, Biophysical Journal, 116(5): 948-961
PDF

Churchill, C. D. M., Winter, P., Tuszynski, J. A., and Levin, M. (2019), EDEn - Electroceutical Design Environment: Ion Channel Tissue Expression Database with Small Molecule Modulators, iScience,11: 42-56
PDF

2018

< Back to Years

Fields, C., and Levin, M. (2018), Multiscale Memory And Bioelectric Error Correction In The Cytoplasm-Cytoskeleton-Membrane System, Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 10(2): e1410 [cover]
PDF

Minh-Thai, T. N., Aryal, J., Samarasinghe, S., and Levin, M. (2018), A Computational Framework for Autonomous Self-repair Systems, in Mitrovic, T., Xue, B., and Li, X. (Eds.), AI 2018: Advances in Artificial Intelligence. Lecture Notes in Computer Science, 11320: 153-159, Springer: Cham
PDF

Adams, D. S., and Levin, M. (2018), Ahead of the Curve: hidden breakthroughs in the biosciences, Vol. 2, IOP Publishing Ltd: Bristol [cover]
Link

Lee, F. J., Williams, K. B., Levin, M., and Wolfe, B. E. (2018), The bacterial metabolite indole inhibits regeneration of the planarian flatworm Dugesia japonica, iScience, 10: 135-148
PDF

Herrera-Rincon, C., Golding, A. S., Moran, K. M., Harrison, C., Martyniuk, C. J., Guay, J. A., Zaltsman, J., Carabello, H., Kaplan, D. L., and Levin, M. (2018), Brief Local Application of Progesterone via a Wearable Bioreactor Induces Long-Term Regenerative Response in Adult Xenopus Hindlimb, Cell Reports, 25(6): 1593-1609
PDF

Kamm, R. D., Bashir, R., Arora, N., Dar, R. D., Gilette, M. U., Griffith, L. G., Kemp, M. L., Kinlaw, K., Levin, M., Martin, A. C., McDevitt, T. C., Nerem, R. M., Powers, M. J., Saif, T. A., Sharpe, J., Takayama, S., Takeuchi, S., Weiss, R., Ye, K., Yevick, H. G., and Zaman, M. H. (2018), Perspective: the promise of multi-cellular engineered living systems, APL Bioengineering, 2(4): 040901
PDF

Cairns, D. M., Giordano, J. E., Conte, S., Levin, M., and Kaplan, D. L. (2018), Ivermectin promotes peripheral nerve regeneration during wound healing, ACS Omega, 3(10): 12392-12402
PDF

Hart, M. R., Anderson, D. J., Porter, C. C., Neff, T., Levin, M., and Horwitz, M. S. (2018), Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations, PLoS Genetics, 14(9): 1007642
PDF

Busse, S. M., McMillen, P. T., and Levin, M. (2018), Cross-limb Communication During Xenopus Hind-limb Regenerative Response: Non-Local Bioelectric Injury Signals, Development, 145(19): dev164210
PDF

Moore, D. G., Walker, S. I., and Levin, M. (2018), Pattern Regeneration in Coupled Networks, in T. Ikegami, N. Virgo, O. Witkowski, M. Oka, R. Suzuki and H. Iizuka (Eds.), ALIFE 2018: The 2018 Conference on Artificial Life. MIT Press: Tokyo, p. 204-205
PDF

Ferreira, G. B. S., Scheutz, M., and Levin, M. (2018), Modeling Cell Migration in a Simulated Bioelectrical Signaling Network for Anatomical Regeneration, in T. Ikegami, N. Virgo, O. Witkowski, M. Oka, R. Suzuki and H. Iizuka (Eds.), ALIFE 2018: The 2018 Conference on Artificial Life. MIT Press: Tokyo, p. 194-201
PDF

Brodsky, M., and Levin, M. (2018), From Physics to Pattern: Uncovering Pattern Formation in Tissue Electrophysiology, in T. Ikegami, N. Virgo, O. Witkowski, M. Oka, R. Suzuki and H. Iizuka (Eds.), ALIFE 2018: The 2018 Conference on Artificial Life. MIT Press: Tokyo, p. 351-358
PDF

Moore, D. G., Valentini, G., Walker, S. I., and Levin, M. (2018), Inform: Efficient Information-Theoretic Analysis of Collective Behaviors, Frontiers in Robotics and AI, 5: 60
PDF

Pezzulo, G., and Levin, M. (2018), Embodying Markov blankets. Comment on 'Answering Schrödinger's question: A free-energy formulation' by Maxwell James Désormeau Ramstead et al., Physics of Life Reviews, 24: 32-36
PDF

Cervera, J., Pietak, A., Levin, M., and Mafe, S. (2018), Bioelectrical coupling in multicellular domains regulated by gap junctions: a conceptual approach, Bioelectrochemistry, 123: 45-61 [cover]
PDF

Pietak, A., and Levin, M. (2018), Bioelectrical control of positional information in development and regeneration: a review of conceptual and computational advances, Progress in Biophysics and Molecular Biology, 137: 52-68
PDF

Mathews, J., and Levin, M. (2018), The Body Electric 2.0: Recent Advances in Developmental Bioelectricity for Regenerative and Synthetic Bioengineering, Current Opinion in Biotechnology, 52: 134-144
PDF

Monsoro-Burq, A. H., and Levin, M. (2018), Avian models and the study of invariant asymmetry: how the chicken and the egg taught us to tell right from left, International Journal of Developmental Biology, 62(1-3): 63-77
PDF

Fields, C., and Levin, M. (2018), Are planaria individuals? What regenerative biology is telling us about the nature of multicellularity, Evolutionary Biology, 45(3): 237-247
PDF

Pai, V. P., Pietak, A., Willocq, V., Ye, B., Shi, N-Q., and Levin, M. (2018), HCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns, Nature Communications, 9(1): 998
PDF

Sullivan, K. G., and Levin, M. (2018), Inverse Drug Screening of Bioelectric Signaling and Neurotransmitter Roles: Illustrated Using a Xenopus Tail Regeneration Assay, Cold Spring Harbor Protocols, 2018(3): 154-163
PDF

Levin, M., and Martyniuk, C. J. (2018), The bioelectric code: An ancient computational medium for dynamic control of growth and form, BioSystems, 164: 76-93
PDF

Cairns, D. M., Boorgu, D. S. S. K., Levin, M., and Kaplan, D. L. (2018), Niclosamide rescues microcephaly in a humanized in vivo model of Zika infection using human induced neural stem cells, Biology Open, 7(1): bio031807
PDF

Herrera-Rincon, C., and Levin, M. (2018), Booting up the organism during development: pre-behavioral functions of the vertebrate brain in guiding body morphogenesis, Communicative & Integrative Biology, 11(1): e1433440 [cover]
PDF

Vallverdu, J., Castro, O., Mayne, R., Talanov, M., Levin, M., Baluška, F., Gunji, Y., Dussutour, A., Zenil, H., and Adamatzky, A. (2018), Slime mould: the fundamental mechanisms of biological cognition, BioSystems, 165: 57-70
PDF

Moore, D. G., Valentini, G., Walker, S. I., and Levin, M. (2018), Inform: a toolkit for information-theoretic analysis of complex systems, Proceedings of the 2017 IEEE Symposium Series on Computational Intelligence (SSCI), p. 3258-3265
PDF

Ferreira, G. B. S., Scheutz, M., and Levin, M. (2018), Introducing Simulated Stem Cells into a Bio-Inspired Cell-Cell Communication Mechanism for Structure Regeneration, Proceedings of the 2017 IEEE Symposium Series on Computational Intelligence (SSCI), p. 2778-2785
PDF

2017

< Back to Years

Tuszynski, J., Tilli, T. M., and Levin, M. (2017), Ion channel and neurotransmitter modulators as electroceutical approaches to the control of cancer, Current Pharmaceutical Design, 23(32): 4827-4841
PDF

Herrera-Rincon, C., Pai, V. P., Moran, K. M., Lemire, J. M., and Levin, M. (2017), The brain is required for normal muscle and nerve patterning during early Xenopus development, Nature Communications, 8(1): 587
PDF

Pitcairn, E., Harris, H., Epiney, J., Pai, V. P., Lemire, J. M., Ye, B., Shi, N-Q., Levin, M., and McLaughlin, K. A. (2017), Coordinating heart morphogenesis: A novel role for Hyperpolarization-activated cyclic nucleotidegated (HCN) channels during cardiogenesis in Xenopus laevis, Communicative & Integrative Biology, 10(3): e1309488 [cover]
PDF

Pietak, A. M., and Levin, M. (2017), Bioelectric Gene and Reaction Networks: Computational Modeling of Genetic, Biochemical, and Bioelectrical Dynamics in Pattern Regulation, Journal of the Royal Society Interface, 14(134): 20170425 [cover]
PDF

McLaughlin, K. A., and Levin, M. (2017), Bioelectric Signaling in Regeneration: Mechanisms of Ionic Controls of Growth and Form, Developmental Biology, 433(2): 177-189
PDF

Pai, V. P., Willocq, V., Pitcairn, E. J., Lemire, J. M., Paré, J-F., Shi, N-Q., McLaughlin, K. A., and Levin, M. (2017), HCN4 Ion Channel Function is Required for Early Events that Regulate Anatomical Left-Right Patterning in a Nodal- and Lefty Asymmetric gene Expression-Independent Manner, Biology Open, 6(10): 1445-1457
PDF

Moore, D., Walker, S. I., and Levin, M. (2017), Cancer as a Disorder of Patterning Information: computational and biophysical perspectives on the cancer problem, Convergent Science Physical Oncology, 3(4): 043001
PDF

Bryant, D. M., Sousounis, K., Farkas, J. E., Bryant, S., Thao, N., Guzikowski, A. R., Monaghan, J. R., Levin, M., and Whited, J. L. (2017), Repeated removal of developing limb buds permanently reduces appendage size in the highly-regenerative axolotl, Developmental Biology, 424(1): 1-9 [cover]
PDF

Adams, D. S., Tseng, A-S., and Levin, M. (2017), Using optogenetics in vivo to stimulate regeneration, in K. Appasani (Ed.), Optogenetics: From Neuronal Function to Mapping and Disease Biology. Cambridge University Press: Cambridge, UK, p. 66-76

Ferreira, G. B., Scheutz, M., and Levin, M. (2017), Investigating the Effects of Noise on a Cell-to-Cell Communication Mechanism for Structure Regeneration, in C. Knibbe, D. Parsons, D. Misevic, J. Rouzaud-Cornaba, N. Bredèche, S. Hassas, O. Simonin, and H. Soula. (Eds.), Proceedings of the 14th European Conference on Artificial Life (ECAL 2017), Lyon, France, p. 170-177
PDF

Zahn, N., Levin, M., and Adams, D. S. (2017), The Zahn Drawings: new illustrations of Xenopus embryo and tadpole stages for studies of craniofacial development, Development, 144(15): 2708-2713 [cover]
PDF

Dungan, J., Mathews, J., Levin, M., and Koomson, V. (2017), Microfluidic Platform to Study Intercellular Connectivity Through on-Chip Electrical Impedance Measurement, IEEE 60th International Midwest Symposium on Circuits and Systems, Boston, MA, p.56-69
PDF

Paré, J-F., Martyniuk, C. J., and Levin, M. (2017), Bioelectric regulation of innate immune system function in regenerating and intact Xenopus laevis, npj Regenerative Medicine, 2: 15
PDF

Durant, F., Morokuma, J., Fields, C., Williams, K., Adams, D. S., and Levin, M. (2017), Long-Term, Stochastic Editing of Regenerative Anatomy via Targeting Endogenous Bioelectric Gradients, Biophysical Journal, 112(10): 2231-2243 [cover]
PDF

Levin, M., Morokuma, J., and Finkelstein, J. (2017), Space travel has effects on planarian regeneration that cannot be explained by a null hypothesis, Regeneration, 4(4): 156-158
PDF

Morokuma, J., Durant, F. R., Williams, K. B., Finkelstein, J. M., Blackiston, D. J., Clements, T., Reed, D. W., Roberts, M., Jain, M., Kimel, K., Trayger, S. A., Wolfe, B. E., and Levin, M. (2017), Planarian regeneration in space: persistent anatomical, behavioral, and bacteriological changes induced by space travel, Regeneration, 4(2): 85-102 [cover]
PDF

Mathews, J., and Levin, M. (2017), Gap Junctional Signaling in Pattern Regulation: physiological network connectivity instructs growth and form, Developmental Neurobiology, 77(5): 643-673
PDF

Levin, M., Pezzulo, G., and Finkelstein, J. M. (2017), Endogenous Bioelectric Signaling Networks: Exploiting Voltage Gradients for Control of Growth and Form, Annual Review of Biomedical Engineering, 19: 353-387
PDF

Thurber, A. E., Nelson, M., Frost, C. L., Levin, M., Brackenbury, W. J., and Kaplan, D. L. (2017), IK channel activation increases tumor growth and induces differential behavioral responses in two breast epithelial cell lines, Oncotarget, 8(26): 42382-42397
PDF

Blackiston, D., Vien, K., and Levin, M. (2017), Serotonergic stimulation induces nerve growth and promotes visual learning via posterior eye grafts in a vertebrate model of induced sensory plasticity, npj Regenerative Medicine, 2: 8
PDF

Lobo, D., Lobikin, M., and Levin, M. (2017), Discovering novel phenotypes with automatically inferred dynamic models: partial melanocyte conversion in Xenopus, Scientific Reports, 7: 41339
PDF

Blackiston, D. J., and Levin, M. (2017), Reversals of bodies, brains, and behavior: quantitative analysis of laterality and its disturbance in model species, in L. J. Rogers and G. Vallortigara (Eds.), Lateralized Brain Functions: Methods in Human and Non-human Species, "Neuromethods", W. Walz (Ed.), 122: 667-694
PDF

Garcia-Quismondo, M., Levin, M., and Lobo, D. (2017), Modeling regenerative processes with Membrane Computing, Information Sciences, 381: 229-249
PDF

Lobo, D., and Levin, M. (2017), Computing a worm: reverse-engineering planarian regeneration, in Adamatzky, A. (Ed), Advances in Unconventional Computing. Emergence, Complexity and Computation, vol 23, Springer: Cham, pp. 637-654

De, Abhishek, Chakravarthy, V. S., and Levin, M. (2017), A Computational Model of Planarian Regeneration, International Journal of Parallel, Emergent, and Distributed Systems, 32(4): 331-347
PDF

2016

< Back to Years

Levin, M., and Adams, D. S. (2016), Ahead of the Curve: Hidden Breakthroughs in the Biosciences, Vol. 1, IOP Publishing: Bristol, UK [cover]

Levin, M., Klar, A. J. S., and Ramsdell, A. (2016), Introduction to provocative questions in Left-Right asymmetry, Philosophical Transactions of the Royal Society B, 371(1710): 20150399
PDF

McDowell, G., Rajadurai, S., and Levin, M. (2016), From cytoskeletal dynamics to organ asymmetry: a nonlinear, regulative pathway underlies left-right patterning, Philosophical Transactions of the Royal Society B, 371(1710): 20150409 [cover]
PDF

Pezzulo, G., and Levin, M. (2016), Top-down models in biology: explanation and control of complex living systems above the molecular level, Journal of the Royal Society Interface, 13(124): 20160555
PDF

Herrera-Rincon, C., Guay, J., and Levin, M. (2016), Bioelectrical coordination of cell activity toward anatomical target states: an engineering perspective on regeneration, Chapter 4 in D. Gardiner (Ed.), Regenerative Engineering and Developmental Biology: Principles and Applications, CRC Press: Boca Raton, FL, p. 55-112
Link

Neuhof, M., Levin, M., and Rechavi, O. (2016), Vertically and horizontally-transmitted memories - the fading boundaries between regeneration and inheritance in planaria, Biology Open, 5(9): 1177-1188 [cover]
PDF

Ferreira, G., Smiley, M., Scheutz, M., and Levin, M. (2016), Dynamic structure discovery and repair for 3D cell assemblages, Proceedings of the Fifteenth International Conference on the Synthesis and Simulation of Living Systems (ALIFEXV), p. 352-359
PDF

Serlin, Z., Rife, J., and Levin, M. (2016), A Level Set Approach to Simulating Xenopus laevis Tail Regeneration, Proceedings of the Fifteenth International Conference on the Synthesis and Simulation of Living Systems (ALIFEXV), p. 528-535
PDF

Pietak, A., and Levin, M. (2016), Exploring Instructive Physiological Signaling with the Bioelectric Tissue Simulation Engine , Frontiers in Bioengineering and Biotechnology, 4: 55
PDF

Baluška, F., and Levin, M. (2016), On Having No Head: Cognition throughout Biological Systems, Frontiers in Psychology, 7: 902
PDF

Pai, V. P., Martyniuk, C. J., Echeverri, K., Sundelacruz, S., Kaplan, D. L., and Levin, M. (2016), Genome-wide analysis reveals conserved transcriptional responses downstream of resting potential change in Xenopus embryos, axolotl regeneration, and human mesenchymal cell differentiation, Regeneration, 3(1): 3-25
PDF

Golding, A., Guay, J. A., Herrera-Rincon, C., Levin, M., and Kaplan, D. L. (2016), A Tunable Silk Hydrogel Device for Studying Limb Regeneration in Adult Xenopus laevis, PLoS One, 11(6): e0155618
PDF

Sullivan, K. G., Emmons-Bell, M., and Levin, M. (2016), Physiological Inputs Regulate Species-Specific Anatomy During Embryogenesis And Regeneration, Communicative & Integrative Biology, 9(4): e1192733 [cover]
PDF

Lobo, D., Morokuma, J., and Levin, M. (2016), Computational discovery and in vivo validation of hnf4 as a regulatory gene in planarian re-generation, Bioinformatics, 32(17): 2681-2685
PDF

Rothman, G., Blackiston, D., and Levin, M. (2016), Color and intensity discrimination in Xenopus laevis tadpoles, Animal Cognition, 19(5): 911-919
PDF

Edelstein, L., Fuxe, K., Levin, M., Popescu, B., and Smythies, J. (2016), Telocytes in their context with other intercellular communication agents, Seminars in Cell and Developmental Biology, 55: 9-13
PDF

Davison, A., McDowell, G. S., Holden, J. M., Johnson, H. F., Koutsovoulos, G. D., Liu, M. M., Hulpiau, P., Van Roy, F., Wade, C. W., Banerjee, R., Yang, F., Chiba, S., Davey, J. W., Jackson, D. J., Levin, M., and Blaxter, M. L., (2016), Formin Is Associated with Left-Right Asymmetry in the Pond Snail and the Frog, Current Biology, 26(5): 654-660 [cover]
PDF

Durant, F., Lobo, D., Hammelman, J., and Levin, M. (2016), Physiological controls of large-scale patterning in planarian regeneration: a molecular and computational perspective on growth and form, Regeneration, 3(2): 78-102 [cover]
PDF

Sullivan, K. G., and Levin, M. (2016), Neurotransmitter signaling pathways required for normal development in Xenopus laevis embryos: a pharmacological survey screen, Journal of Anatomy, 229(4): 483-502 [cover]
PDF

Chernet, B. T., Adams, D. S., Lobikin, M., and Levin, M. (2016), Use of genetically encoded, light-gated ion translocators to control tumorigenesis, Oncotarget, 7(15): 19575-19588
PDF

Adams, D. S., Uzel, S. G. M., Akagi, J., Wlodkowic, D., Andreeva, V., Yelick, P. C., Devitt-Lee, A., Paré, J-F., and Levin, M. (2016), Bioelectric signaling via potassium channels: a mechanism for craniofacial dysmorphogenesis in KCNJ2-associated Andersen-Tawil Syndrome, Journal of Physiology, 594(12): 3245-3270 [cover]
PDF

McDowell, G. S., Lemire, J. M., Paré, J-F., Cammarata, G., Lowery, L. A., and Levin, M. (2016), Conserved roles for cytoskeletal components in determining laterality, Integrative Biology, 8(3): 267-286 [cover]
PDF

Li, C., Levin, M., and Kaplan, D. (2016), Bioelectric modulation of macrophage polarization, Scientific Reports, 6: 21044
PDF

Dimonte, A., Adamatzky, A., Erokhin, V., and Levin, M. (2016), On chirality of slime mould, BioSystems, 140: 23-27
PDF

Lobo, D., Hammelman, J., and Levin, M. (2016), MoCha: molecular characterization of unknown pathways, Journal of Computational Biology, 23(4): 291-297
PDF

Whiting, J. G. H., Jones, J., Bull, L., Levin, M., and Adamatzky, A. (2016), Towards a physarum learning chip, Scientific Reports, 6: 19948
PDF

Hammelman, J., Lobo, D., and Levin, M. (2016), Artificial neural networks as models of robustness in development and regeneration: stability of memory during morphological remodeling, in S. Shanmuganathan and S. Samarasinghe (Eds.), Artificial Neural Network (ANN) Modeling. Studies in Computational Intelligence, vol. 628, pp. 45-65
PDF

2015

< Back to Years

Sundelacruz, S., Levin M., and Kaplan, D. L. (2015), Comparison of the depolarization response of human mesenchymal stem cells from different donors, Scientific Reports, 5: 18279
PDF

Emmons-Bell, M., Durant, F., Hammelman, J., Bessonov, N., Volpert, V., Morokuma, J., Pinet, K., Adams, D. S., Pietak, A., Lobo, D., and Levin, M. (2015), Gap junctional blockade stochastically induces different species-specific head anatomies in genetically wild-type Girardia dorotocephala flatworms, International Journal of Molecular Sciences, 16(11): 27865-27896 [cover]
PDF

Pezzulo, G., and Levin, M. (2015), Re-membering the body: applications of computational neuroscience to the top-down control of regeneration of limbs and other complex organs, Integrative Biology, 7(12): 1487-1517 [cover]
PDF

Pang, J., Özkucur, N., Ren, M., Kaplan, D. L., Levin, M., and Miller, E. L. (2015), Automatic neuron segmentation and neural network analysis method for phase contrast microscopy images, Biomedical Optics Express, 6(11): 4395-4416
PDF

Lobikin, M., Lobo, D., Blackiston, D. J., Martyniuk, C. J., Tkachenko, E., and Levin, M. (2015), Serotonergic regulation of melanocyte conversion: A bioelectrically regulated network for stochastic all-or-none hyperpigmentation, Science Signaling, 8(397): ra99
PDF

Law, R., and Levin, M. (2015), Bioelectric memory: modeling resting potential bistability in amphibian embryos and mammalian cells, Theoretical Biology and Medical Modelling, 12(1): 22
PDF

Schatzberg, D., Lawton, M., Hadyniak, S. E., Ross E. J., Carney, T., Beane, W. S., Levin, M., and Bradham, C. A. (2015), H+/K+-ATPase activity is required for biomineralization in sea urchin embryos, Developmental Biology, 406(2): 259-270
PDF

Bessonov, N., Levin, M., Morozova, N., Reinberg, N., Tosenberger, A., and Volpert, V. (2015), Target morphology and cell memory: a model of regenerative pattern formation, Neural Regeneration Research, 10(12): 1901-1905 [cover]
PDF

Blackiston, D. J., Shomrat, T., and Levin, M. (2015), The Stability of Memories During Brain Remodeling: a Perspective, Communicative & Integrative Biology, 8(5): e1073424 [cover]
PDF

Pai, V. P., Lemire, J. M., Chen, Y., Lin, G., and Levin, M. (2015), Local and long-range endogenous resting potential gradients antagonistically regulate apoptosis and proliferation in the embryonic CNS, International Journal of Developmental Biology, 59(7-9): 327-340
PDF

Lobikin, M., Paré, J-F., Kaplan, D. L., and Levin, M. (2015), Selective Depolarization Of Transmembrane Potential Alters Muscle Patterning And Muscle Cell Localization In Embryonic Xenopus Laevis, International Journal of Developmental Biology, 59(7-9): 303-311 [cover]
PDF

Lobo, D., and Levin, M. (2015), Inferring regulatory networks from experimental morphological phenotypes: a computational method reverse-engineers planarian regeneration, PLoS Computational Biology, 11(6): e1004295
PDF

Tosenberger, A., Bessonov, N., Levin, M., Reinberg, N., Volpert, V., and Morozova, N. (2015), A conceptual model of morphogenesis and regeneration, Acta Biotheoretica, 63(3): 283-294
PDF

Levin, M. (2015), Gap junctions: versatile mediators of long-range developmental signals, The Node
Full text

Levin, M. (2015), Nerves read the electrical typography of their microenvironment in making growth decisions, The Node
Full text

Friston, K., Levin, M., Sengupta, B., and Pezzulo, G. (2015), Knowing one's place: a free energy approach to pattern regulation, Journal of the Royal Society Interface, 12(105): 20141383
PDF

Pai, V., Lemire, J. M., Paré, J-F., Lin, G., Chen, Y., and Levin, M. (2015), Endogenous gradients of resting potential instructively pattern embryonic neural tissue via Notch signaling and regulation of proliferation, Journal of Neuroscience, 35(10): 4366-4385
PDF

Özkucur, N., Quinn, K. P., Pang, J. C., Du, C., Georgakoudi, I., Miller, E., Levin, M., and Kaplan, D. L. (2015), Membrane potential depolarization causes alterations in neuron arrangement and connectivity in cocultures, Brain and Behavior, 5(1): 24-38
PDF

Bessonov, N., Levin, M., Morozova, N., Reinberg, N., Tosenberger, A., and Volpert, V. (2015), On a model of pattern recognition based on cell memory, PLoS One, 10(2): e0118091
PDF

Blackiston, D., Anderson, G. M., Rahman, N., Bieck, C., and Levin, M. (2015), A novel method for inducing nerve growth via modulation of host resting potential, Neurotherapeutics, 12(1): 170-184
PDF

Chernet, B. T., Fields, C., and Levin, M. (2015), Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos, Frontiers in Physiology, 5: 519
PDF

2014

< Back to Years

Levin, M. (2014), Molecular bioelectricity: how endogenous voltage potentials control cell behavior and instruct pattern regulation in vivo, Molecular Biology of the Cell, 25(24): 3835-3850
PDF

Jewhurst, K., Levin, M., and McLaughlin, K. A. (2014), Optogenetic Control of Apoptosis in Targeted Tissues of Xenopus laevis Embryos, Journal of Cell Death, 7: 25-31
PDF

Adams, D. S., Lemire, J. M., Kramer, R. H., and Levin, M. (2014), Optogenetics in developmental biology: using light to control ion flux-dependent signals in Xenopus embryos, International Journal of Developmental Biology, 58(10-12): 851-861
PDF

Vandenberg, L. N., Blackiston, D. J., Rea, A. C., Dore, T. M., and Levin, M. (2014), Left-right patterning in Xenopus conjoined twin embryos requires serotonin signaling and gap junctions, International Journal of Developmental Biology, 58(10-12): 799-809
PDF

Zhu, F., Skommer, J., Huang, Y., Akagi, J., Adams, D. S., Levin, M., Hall, C. J., Crosier, P. S., and Wlodkowic, D. (2014), Fishing on chips: up-and-coming technological advances in analysis of zebrafish and Xenopus embryos, Cytometry A, 85A(11): 921-932
PDF

Lobo, D., Feldman, E. B., Shah, M., Malone, T. J., and Levin, M. (2014), Limbform: a functional ontology-based database of limb regeneration experiments, Bioinformatics, 30(24): 3598-3600
PDF

Lan, J. Y., Williams, C., Levin, M., and Black, L. D. III (2014), Depolarization of Cellular Resting Membrane Potential Promotes Neonatal Cardiomyocyte Proliferation In Vitro, Cellular and Molecular Bioengineering, 7(3): 432-445
PDF

Mustard, J., and Levin, M. (2014), Bioelectrical mechanisms for programming growth and form: taming physiological networks for soft body robotics, Soft Robotics, 1(3): 169-191
PDF

Lobo, D., Feldman, E. B., Shah, M., Malone, T., and Levin, M. (2014), A bioinformatics expert system linking functional data to anatomical outcomes in limb regeneration, Regeneration, 1(2): 37-56
PDF

Budnikova, M., Habig, J. W., Cornia, N., Levin, M., Lobo, D., and Andersen, T. (2014), Design of a flexible component gathering algorithm forconverting cell-based models to graph representations for use inevolutionary search, BMC Bioinformatics, 15(1): 178
PDF

Chernet, B., and Levin, M. (2014), Transmembrane voltage potential of somatic cells controls oncogene-mediated tumorigenesis at long-range, Oncotarget, 5(10): 3287-3306 [cover]
PDF

Hernandez-Diaz, S., and Levin, M. (2014), Alteration of bioelectrically-controlled processes in the embryo: a teratogenic mechanism for anticonvulsants, Reproductive Toxicology, 47: 111-114
PDF

Pai, V., and Levin, M. (2014), Bioelectric controls of stem cell function, Chapter 5 in F. Calegari and C. Waskow (Eds.), Stem Cells: From Basic Research to Therapy, Volume 1, CRC Press: Boca Raton, FL, pp. 106-148
Amazon book

Levin, M. (2014), Endogenous bioelectrical networks store non-genetic patterning information during development and regeneration, Journal of Physiology, 592(11): 2295-2305
PDF

Lobo, D., Solano, M., Bubenik, G. A., and Levin, M. (2014), A linear-encoding model explains the variability of the target morphology in regeneration, Journal of the Royal Society Interface, 11(92): 20130918
PDF

Lobikin, M., and Levin, M. (2014), Endogenous bioelectric cues as morphogenetic signals in vivo, Chapter 15 in D. Fels, M. Cifra, and F. Scholkmann (Eds), Fields of the Cell, Research Signpost: Kerala, India, pp. 283-302
PDF

Lange, C., Prenninger, S., Knuckles, P., Taylor, V., Levin, M., and Calegari, F. (2014), V-ATPase maintains neural stem cells in the developing mouse cortex, in S. Nakamuri (Ed.), Handbook of H+ ATPases, Pan Stanford Pte. Ltd: Singapore, pp. 413-430
PDF

2013

< Back to Years

Vandenberg, L. N., Lemire, J. M, and Levin, M. (2013), It's Never too Early to get it Right: A Conserved Role for the Cytoskeleton in Left-Right Asymmetry, Communicative & Integrative Biology, 6(6): e27155
PDF

Levin, M. (2013), Remembrance of Brains Past, The Node
Full text

Rea, A. C., Vandenberg, L. N., Ball, R. E., Snouffer, A. A., Hudson, A. G., Zhu, Y., McLain, D. E., Johnston, L. L., Lauderdale J. D., Levin, M., and Dore, T. M. (2013), Light-activated serotonin for exploring its action in biological systems, Chemistry & Biology, 20(12): 1536-1546
PDF

Sundelacruz, S., Li, C., Choi, Y. J., Levin, M., and Kaplan, D. L. (2013) Bioelectric modulation of wound healing in a 3D in vitro model of tissue-engineered bone, Biomaterials, 34(28): 6695-705
PDF

Sundelacruz, S., Levin, M., and Kaplan, D. L. (2013), Depolarization Alters Phenotype, Maintains Plasticity of Predifferentiated Mesenchymal Stem Cells, Tissue Engineering Part A, 19(17-18): 1889-1908
PDF

Chernet, B., and Levin, M. (2013), Endogenous voltage potentials and the microenvironment: bioelectric signals that reveal, induce, and normalize cancer, Journal of Clinical and Experimental Oncology, S1: doi:10.4172/2324-9110.S1-002 [cover]
PDF

Levin, M. (2013), Reprogramming cells and tissue patterning via bioelectrical pathways: molecular mechanisms and biomedical opportunities, Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 5(6): 657-676
PDF

Shomrat, T., and Levin, M. (2013), An automated training paradigm reveals long-term memory in planaria and its persistence through head regeneration, Journal of Experimental Biology, 216(20): 3799-3810
PDF | Overview

Levin, M. (2013), Bioelectrical signaling has rich history, Physics Today, 66(9): 11
PDF

Blackiston, D. J., and Levin, M. (2013), Inversion of left-right asymmetry alters performance of Xenopus tadpoles in nonlateralized cognitive tasks, Animal Behaviour, 86(2): 459-466
PDF

Vandenberg, L. N., and Levin, M. (2013), A unified model for left-right asymmetry? Comparison and synthesis of molecular models of laterality, Developmental Biology, 379(1): 1-15 [cover]
PDF

Lobo, D., Malone, T. J., and Levin, M. (2013), Towards a bioinformatics of patterning: a computational approach to understanding regulative morphogenesis, Biology Open, 2(2): 156-169 [cover]
PDF

Vandenberg, L. N., Morrie, R. D., Seebohm, G., Lemire, J. M., and Levin, M. (2013), Rab GTPases are required for early orientation of the left-right axis in Xenopus, Mechanisms of Development, 130(4-5): 254-271 [cover]
PDF

Adams, D. S., and Levin, M. (2013), Endogenous Voltage Gradients as Mediators of Cell-Cell Communication: Strategies for Investigating Bioelectrical Signals During Pattern Formation, Cell and Tissue Research, 352(1):95-122 [cover]
PDF

Blackiston, D. J., and Levin, M. (2013), Ectopic eyes outside the head in Xenopus tadpoles provide sensory data for light-mediated learning, Journal of Experimental Biology, 216(6): 1031-1040
PDF

Lobo, D., Malone, T. J., and Levin, M. (2013), Planform: an application and database of graph-encoded planarian regenerative experiments, Bioinformatics, 29(8): 1098-1100
PDF

Koustubhan, P., Kaplan, D., and Levin, M. (2013), Humane anesthesia and pain management in amphibian limb surgery of Rana pipiens, Cold Spring Harbor Protocols, 2013(2): 149-155 [cover]
PDF

Chernet, B. T., and Levin, M. (2013), Transmembrane voltage potential is an essential cellular parameter for the detection and control of tumor development in a Xenopus model, Disease Models & Mechanisms, 6(3): 595-607
PDF

Tseng, A-S., and Levin, M. (2013), Cracking the bioelectric code: probing endogenous ionic controls of pattern formation, Communicative & Integrative Biology, 6(1): e22595 [cover]
PDF

Adams, D. S., Tseng, A-S. and Levin, M. (2013), Light-activation of the Archaerhodopsin H+ pump reverses age-dependent loss of vertebrate regeneration: sparking system-level controls in vivo, Biology Open, 2(3): 306-313
PDF

Vandenberg, L. N., Lemire, J. M., and Levin, M. (2013), Serotonin has early, cilia-independent roles in Xenopus left-right patterning, Disease Models and Mechanisms, 6(1): 261-268 [cover]
PDF

Beane, W. S., Morokuma, J., Lemire, J. M., and Levin, M. (2013), Bioelectric signaling regulates head and organ size during planarian regeneration, Development, 140(2): 313-322
PDF

2012

< Back to Years

Vandenberg, L. N., Stevenson, C., and Levin, M. (2012), Low frequency vibrations induce malformations in two aquatic species in a frequency-, waveform-, and direction-specific manner, PLoS One, 7(12): e51473
PDF

Pai, V. P., Vandenberg, L. N., Blackiston, D. J., and Levin, M. (2012), Neurally derived tissues in Xenopus laevis embryos exhibit a consistent bioelectrical left-right asymmetry, Stem Cells International, 2012: 353491
PDF

Lobikin, M., Chernet, B., Lobo, D., and Levin, M. (2012), Resting potential, oncogene-induced tumorigenesis, and metastasis: the bioelectric basis of cancer in vivo, Physical Biology, 9(6): 065002 [cover]
PDF

Lobikin, M., Wang, G., Xu, J.-S., Hsieh, Y.-W., Chuang, C.-F., Lemire, J. M., and Levin, M. (2012), Early, nonciliary role for microtubule proteins in left-right patterning is conserved across kingdoms, Proceedings of the National Academy of Sciences of the United States, 109(31): 12586-12591
PDF

Tseng, A.-S., and Levin, M. (2012), Transducing bioelectrical signals into epigenetic pathways during tadpole tail regeneration, Anatomical Record, 295(10): 1541-1551
PDF

Levin, M. (2012), Morphogenetic fields in embryogenesis, regeneration, and cancer: non-local control of complex patterning, BioSystems, 109(3): 243-261
PDF

Vandenberg, L. N., Adams, D. S., and Levin, M. (2012), Normalized shape and location of perturbed craniofacial structures in the Xenopus tadpole reveal an innate ability to achieve correct morphology, Developmental Dynamics, 241(5): 863-878 [cover]
PDF

Blackiston, D. J., and Levin, M. (2012), Aversive training methods in Xenopus laevis: general principles, Cold Spring Harbor Protocols, 2012(5): 521-527
PDF

Beane, W. S., Tseng, A.-S., Morokuma, J. M., Lemire, J. M., and Levin, M. (2012), Inhibition of planar cell polarity extends neural growth during regeneration, homeostasis, and development, Stem Cells and Development, 21(12): 2085-2094 [cover]
PDF

Chernet, B. T., Adams, D. S., and Levin, M. (2012), Photoconversion for Tracking the Dynamics of Cell Movement in Xenopus laevis Embryos, Cold Spring Harbor Protocols, 2016(6): 683-690 [cover]
PDF

Chernet, B. T., and Levin, M. (2012), A versatile protocol for mRNA electroporation of Xenopus laevis embryos, Cold Spring Harbor Protocols, 2012(4): 447-452
PDF

Adams, D. S., and Levin, M. (2012), General principles for measuring resting membrane potential and ion concentration using fluorescent bioelectricity reporters, Cold Spring Harbor Protocols, 2012(4): 385-397 [cover]
PDF

Adams, D. S., and Levin, M. (2012), Measuring resting membrane potential using the fluorescent voltage reporters DiBAC₄(3) and CC2-DMPE, CSHL Protocols, 2012(4): 459-464
PDF

Pai, V., Aw, S., Shomrat, T., Lemire, J. M., and Levin, M. (2012), Transmembrane voltage potential controls embryonic eye patterning in Xenopus laevis, Development, 139(2): 313-323
PDF

Levin, M. (2012), Molecular bioelectricity in developmental biology: new tools and recent discoveries, BioEssays, 34(3): 205-217 [cover]
PDF

Vandenberg, L. N., and Levin, M. (2012), Polarity proteins are required for left-right axis orientation and twin-twin instruction,Genesis, 50(3): 219-234
PDF

Levin, M., and Stevenson, C. (2012), Regulation of Cell Behavior and Tissue Patterning by Bioelectrical Signals: challenges and opportunities for biomedical engineering, Annual Reviews in Biomedical Engineering, 14: 295-323
PDF

Lobo, D., Beane, W., and Levin, M. (2012), Modeling planarian regeneration: a primer for reverse-engineering the worm, PLoS Computational Biology, 8(4): e1002481 [cover]
PDF

2011

< Back to Years

Blackiston, D., Adams, D. S., Lemire, J. M., Lobikin, M., and Levin, M. (2011), Transmembrane potential of GlyCl-expressing instructor cells induces a neoplastic-like conversion of melanocytes via a serotonergic pathway, Disease Models and Mechanisms, 4(1): 67-85 [cover]
PDF

Beane, W. S., Morokuma, J., Adams, D. S., and Levin, M. (2011),A chemical genetics approach reveals H,K-ATPase-mediated membrane voltage is required for planarian head regeneration, Chemistry & Biology, 18(1): 77-89
PDF

Lange, C., Prenninger, S., Knuckles, P., Taylor, V., Levin, M., and Calegari, F. (2011), The H(+) vacuolar ATPase maintains neural stem cells in the developing mouse cortex, Stem Cells and Development, 20(5): 843-850
PDF

Carneiro, K., Donnet, C., Rejtar, T., Karger, B. L., Díaz, E., Kortagere, S., Lemire, J. M., and Levin, M. (2011), Histone deacetylase activity is necessary for left-right patterning during vertebrate development, BMC Developmental Biology, 11: 29
PubMed | PDF

Vandenberg, L. N., Pennarola, B. W., and Levin, M. (2011), Low frequency vibrations disrupt left-right patterning in the Xenopus embryo, PLoS One, 6(8): e23306
PDF

Mondia, J. P., Adams, D. S., Orendorff, R. D., Levin, M., and Omenetto, F. (2011), Patterned femtosecond-laser ablation of Xenopus laevis melanocytes for studies of cell migration, wound repair, and developmental processes, Biomedical Optics Express, 2(8): 2383-2391
PDF

Mondia, J. P., Levin, M., Omenetto, F. G., Orendorff, R. D., Branch, M. R., and Adams, D. S. (2011), Long-distance signals are required for morphogenesis of the regenerating Xenopus tadpole tail as shown by femtosecond-laser ablation, PLoS One, 6(9): e24953
PDF

Tseng, A-S., Carneiro, K., Lemire, J. M., and Levin, M. (2011),HDAC activity is required during Xenopus tail regeneration, PLoS One, 6(10): e26382
PDF

Levin, M. (2011), Endogenous Bioelectric Signals as Morphogenetic Controls of Development, Regeneration, and Neoplasm, in C. Pullar (Ed.), The Physiology of Bioelectricity in Development, Tissue Regeneration, and Cancer, CRC Press: Boca Raton, FL, pp. 39-89
Available here

Levin, M. (2011), The wisdom of the body: future techniques and approaches to morphogenetic fields in regenerative medicine, developmental biology, and cancer, Regenerative Medicine, 6(6): 667-673
PDF

2010

< Back to Years

Blackiston, D., Shomrat, T., Nicolas, C. L., Granata, C., and Levin, M. (2010), A second-generation device for automated training and quantitative behavior analyses of molecularly-tractable model organisms, PLoS One, 5(12): e14370
PDF

Oviedo, N. J., Morokuma, J., Walentek, P., Kema, I. P., Gu, M. B., Ahn, J. M., Hwang, J. S., Gojobori, T., and Levin, M. (2010), Long-range Neural and Gap Junction Protein-mediated Cues Control Polarity During Planarian Regeneration, Developmental Biology, 339(1): 188-199 [cover]
PDF

Vandenberg, L. N., and Levin, M. (2010), Consistent left-right asymmetry cannot be Established by late organizers in Xenopus unless the late organizer is a conjoined twin, Development, 137(7): 1095-1105 [cover]
PDF

Aw, S., Koster, J., Pearson, W., Nicols, C., Shi, N. Q., Carneiro, K., and Levin, M. (2010), The ATP-sensitive K+-channel (KATP) controls early left-right patterning in Xenopus and chick embryos, Developmental Biology, 346(1): 39-53
PDF

Tseng, A-S., Beane, W. S., Lemire, J. M., Masi, A., and Levin, M. (2010), Induction of vertebrate regeneration by a transient sodium current, Journal of Neuroscience, 30(39): 13192-13200 [cover]
PDF

Hechavarria, D., Dewilde, A., Braunhut, S., Levin, M., and Kaplan, D. K. (2010), BioDome regenerative sleeve for biochemical and biophysical stimulation of tissue regeneration, Medical Engineering and Physics, 32(9): 1065-1073
PDF

Blackiston, D., Vandenberg, L. N., and Levin, M. (2010), High-throughput Xenopus laevis immunohistochemistry using agarose sections, Cold Spring Harbor Protocols, 2010(12): 1364-1371
PDF

Vandenberg, L. N., and Levin, M. (2010), Far from solved: a perspective on what we know about early mechanisms of left-right asymmetry, Developmental Dynamics, 239(12): 3131-3146 [cover]
PDF

2009

< Back to Years

Aw, S., and Levin, M. (2009), Molecular mechanisms establishing consistent left-right asymmetry during vertebrate embryogenesis, in I. E. C Sommer and R. S. Kahn (Eds.), Language Lateralization and Psychosis, Cambridge University Press: Cambridge, UK, 3-18
PDF

Aw, S., and Levin, M. (2009), Is left-right asymmetry a form of planar cell polarity? Development, 136(3): 355-366
PDF

Vandenberg, L., and Levin, M. (2009), Perspectives and open problems in the early phases of left-right patterning, Seminars in Cell and Developmental Biology, 20(4): 456-463 [cover]
PDF

Zhang, Y., and Levin, M. (2009), Particle tracking model of electrophoretic morphogen movement reveals stochastic dynamics of embryonic gradient, Developmental Dynamics, 238(8): 1923-1935
PDF

Zhang, Y., and Levin, M. (2009), Left-right asymmetry in the chick embryo requires core planar cell polarity protein Vangl2, Genesis, 47(11): 719-728
PDF

Levin, M. (2009), Bioelectric mechanisms in regeneration: Unique aspects and future perspectives, Seminars in Cell and Developmental Biology, 20(5): 543-556
PDF

Sundelacruz, S., Levin, M., and Kaplan, D. L. (2009), Role of membrane potential in the regulation of cell proliferation and differentiation, Stem Cell Reviews, 5(3): 231-246
PDF

Blackiston, D. J., McLaughlin, K., and Levin, M. (2009), Bioelectric controls of cell proliferation: ion channels, membrane voltage, and the cell cycle, Cell Cycle, 8(21): 3527-3536 [cover]
PDF

2008

< Back to Years

Morokuma, J., Blackiston, D., and Levin, M. (2008), KCNQ1 and KCNE1 K+ channel components are involved in early left-right patterning in Xenopus embryos, Cellular Physiology and Biochemistry, 21(5-6): 357-372
PDF

Oviedo, N. J., Pearson, B. J., Levin, M., and Alvarado, A. S. (2008), Planarian PTEN homologs regulate stem cells and regeneration through TOR signaling, Disease Models and Mechanisms, 1(2-3): 131-143
PDF

Morokuma, J., Blackiston, D., Adams, D. S., Seebohm, G., Trimmer, B., and Levin, M. (2008), Modulation of potassium channel confers a hyperproliferative invasive phenotype on embryonic stem cells, Proceedings of the National Academy of Sciences of the United States, 105(43): 16608-16613
PDF

Sundelacruz, S., Levin, M., and Kaplan, D. L. (2008), Membrane potential controls adipogenic and osteogenic differentiation of mesenchymal stem cells, PLoS One, 3(11): e3737
PDF

Oviedo, N. J., Nicolas, C. L., Adams, D. S., and Levin, M. (2008), Live imaging of planarian membrane potential using DiBAC4(3), Cold Spring Harbor Protocols, 3(10): pdb.prot5055
PDF

Oviedo, N. J., Nicolas, C. L., Adams, D. S., and Levin, M. (2008), Gene knockdown in planarians using RNA interference, Cold Spring Harbor Protocols, 3(10): pdb.prot5054
PDF

Oviedo, N. J., Nicolas, C. L., Adams, D. S., and Levin, M. (2008), Establishing and maintaining a colony of planarians, Cold Spring Harbor Protocols, 3(10): pdb.prot5053
PDF

Oviedo, N., and Levin, M. (2008), The planarian regeneration model as a context for the study of drug effects and mechanisms, in R. B. Raffa & S. M. Rawls (Eds.), Planaria: A Model for Drug Action and Abuse, RG Landes Co.: Austin, pp. 95-104

Nicolas, C.L., Abramson, C.I., and Levin, M. (2008), Analysis of behavior in the planarian model, in R. B. Raffa & S. M. Rawls (Eds.), Planaria: A Model for Drug Action and Abuse, RG Landes Co.: Austin, pp. 83-94

Aw, S., and Levin, M. (2008), What's Left in Asymmetry? Developmental Dynamics, 237(12): 3453-3464
PDF

Oviedo, N., Nicolas, C. L., Adams, D. S., and Levin, M. (2008), Planarians: a versatile and powerful model system for molecular studies of regeneration, adult stem cell regulation, aging, and behavior, Cold Spring Harbor Protocols, 3(10): pdb.em0101
PDF

Oviedo, N., Nicolas, C. L., Adams, D. S., and Levin, M. (2008),Planarians: a versatile and powerful model system for molecular studies of regeneration, adult stem cell regulation, aging, and behavior, in Emerging Model Organisms: A Laboratory Manual, Volume 1, Cold Spring Harbor Press: Cold Spring Harbor, NY
PDF | Book

Tseng, A-S., and Levin, M. (2008), Tail regeneration in Xenopus laevis as a model for understanding tissue repair, Journal of Dental Research, 87(9): 806-816
PDF

2007

< Back to Years

Tseng, A-S., Adams, D. S., Qiu, D., Koustubhan, P., and Levin, M. (2007), Apoptosis is required during early stages of tail regeneration in Xenopus laevis, Developmental Biology, 301(1): 62-69
PDF

Adams, D. S., Masi, A., and Levin, M. (2007), H+ Pump-dependent changes in membrane voltage are an early mechanism necessary and sufficient to induce Xenopus tail regeneration, Development, 134(7): 1323-1335 [cover]
PDF

Oviedo, N. J., and Levin, M. (2007), smedxin-11 is a Planarian Stem Cell Gap Junction Gene Required for Regeneration and Homeostasis, Development, 134(17): 3121-3131
PDF

Aw, S., Adams, D. S., Qiu, D., and Levin, M. (2007), H,K-ATPase protein localization and Kir4.1 function reveal concordance of three axes during early determination of left-right asymmetry, Mechanisms of Development, 125(3-4): 353-372
PDF

Koustubhan, P., Sorocco, D., and Levin, M. (2007), Establishing and maintaining a Xenopus laevis colony for research laboratories, in P. M. Conn (Ed.), Source Book of Models for Biomedical Research, Humana Press: Totowa NJ, pp. 139-160
PDF

Levin, M., and Palmer, R. (2007), Left-right patterning from the inside out: widespread evidence for intracellular control, BioEssays, 29(3): 271-287
PDF

Levin, M. (2007), Gap junctional communication in morphogenesis, Progress in Biophysics and Molecular Biology, 94(1-2): 186-206
PDF

Levin, M. (2007), Large-Scale Biophysics: Ion Flows and Regeneration, Trends in Cell Biology, 17(6): 261-270 [cover]
PDF

Ingber, D., and Levin, M. (2007), What lies at the interface of regenerative medicine and developmental biology? Development, 134(14): 2541-2547 [cover]
PDF

Oviedo, N., and Levin, M. (2007), Gap junctions provide new links in left-right patterning, Cell, 129(4): 645-647
PDF

2006

< Back to Years

Hibino, T., Ishii, Y., Levin, M., and Nishino, A. (2006), Ion flow regulates left-right asymmetry in sea urchin development, Development Genes and Evolution, 216(5): 265-76
PDF

Shimeld, S. M., and Levin, M. (2006), Evidence for the regulation of left-right asymmetry in Ciona intestinalis by ion flux, Developmental Dynamics, 235(6): 1543-1553
PDF

Adams, D. S., Robinson, K. R., Fukumoto, T., Yuan, S., Albertson, R. C., Yelick, P., Kuo, L., McSweeney, M., and Levin, M. (2006), Early, H+-V-ATPase-dependent proton flux is necessary for consistent left-right patterning of non-mammalian vertebrates, Development, 133(9): 1657-1671
PDF

Hicks, C., Sorocco, D., and Levin, M. (2006), Automated Analysis of Behavior: A Computer-Controlled System for Drug Screening and the Investigation of Learning, Journal of Neurobiology, 66(9): 977-990
PDF

Esser, A. T., Smith, K. C., Weaver, J. C., and Levin, M. (2006), Mathematical Model of Morphogen Electrophoresis through Gap Junctions, Developmental Dynamics, 235(8): 2144-2159
PDF

Adams, D. S., and Levin, M. (2006), Inverse Drug Screens: a rapid and inexpensive method for implicating molecular targets, Genesis, 44(11): 530-540
PDF

Adams, D., and Levin, M. (2006), Strategies and techniques for investigation of biophysical signals in patterning, in Analysis of Growth Factor signaling in Embryos, M. Whitman and A. K. Sater eds., pp. 177-264, Methods in Signal Transduction Series, CRC Press

Levin, M., Buznikov, G. A., and Lauder, J. M. (2006), Of Minds and Embryos: Left-Right Asymmetry and the Serotonergic Controls of Pre-Neural Morphogenesis, Developmental Neuroscience, 28(3): 171-185 [cover]
PDF

Levin, M. (2006), Is the Early Left-Right Axis like a Plant, a Kidney, or a Neuron? The Integration of Physiological Signals in Left-Right Asymmetry, Birth Defects Research (Part C), 78(3): 191-223
PDF

2005

< Back to Years

Fukumoto, T., and Levin, M. (2005), Asymmetric expression of Syndecan-2 in early chick embryogenesis, Gene Expression Patterns , 5(4): 525-528
PDF

Fukumoto, T., Kema, I. P., and Levin, M. (2005), Serotonin signaling is a very early step in patterning of the left-right axis in chick and frog embryos, Current Biology, 15(9): 794-803
PDF

Nogi, T., Yuan, Y. E., Sorocco, D., Perez-Tomas, R., and Levin, M. (2005), Eye regeneration assay reveals an invariant functional left-right asymmetry in the early bilaterian, Dugesia japonica, Laterality, 10(3): 193-205
PDF

Qiu, D., Cheng, S. M., Wozniak, L., McSweeney, M., Perrone, E., and Levin, M. (2005), Localization and loss-of-function implicates ciliary proteins in early, cytoplasmic roles in left-right asymmetry, Developmental Dynamics, 234(1): 176-189
PDF

Shin, J-B., Adams, D., Paukert, M., Siba, M., Sidi, S., Levin, M., Gillespie, P. G., and Grunder, S. (2005), Xenopus TRPN1 (NOMPC) localizes to microtubule-based cilia in epithelial cells, including inner-ear hair cells, Proceedings of the National Academy of Sciences of the United States, 102(35): 12572-12577
PDF

Gamer, L. W., Nove, J., Levin, M., and Rosen, V. (2005), BMP-3 is a novel inhibitor of both activin and BMP-4 signaling in Xenopus embryos, Developmental Biology, 285(1): 156-168
PDF

Nogi, T., and Levin, M. (2005), Characterization of innexin gene expression and functional roles of gap-junctional communication in planarian regeneration, Developmental Biology, 287(2): 314-335
PDF

Fukumoto, T., Blakely, R., and Levin, M. (2005), Serotonin transporter function is an early step in left-right patterning in chick and frog embryos, Developmental Neuroscience, 27(6): 349-363
PDF

Levin, M. (2005), Left-right asymmetry in embryonic development: a comprehensive review, Mechanisms of Development, 122(1): 3-25 [cover]
PDF

2004

< Back to Years

Levin, M. (2004), A novel immunohistochemical method for evaluation of antibody specificity and detection of labile targets in biological tissue, Journal of Biophysical and Biochemical Methods, 58(1): 85-96
PDF

Levin, M. (2004), The embryonic origins of left-right asymmetry, Critical Reviews in Oral Biology and Medicine, 15(4): 197-206
PDF

Adams, D. S., and Levin, M. (2004), Early Patterning of the Left/Right Axis, in C. D. Stern (Ed.), Gastrulation: from cells to embryo, Cold Spring Harbor: New York, pp. 403-417
PDF

2003

< Back to Years

Bunney, T. D., De Boer, A. H., and Levin, M. (2003), Fusicoccin signaling reveals 14-3-3 protein function as a novel step in left-right patterning during amphibian embryogenesis, Development, 130(20): 4847-4858
PDF

Levin, M. (2003), Bioelectromagnetics in morphogenesis, Bioelectromagnetics, 24(5): 295-315
PDF

Levin, M. (2003), Motor protein control of ion flux is an early step in embryonic left-right asymmetry, BioEssays, 25(10): 1002-1010
PDF

2002

< Back to Years

Levin, M., Thorlin, T., Robinson, K., Nogi, T., and Mercola, M. (2002), Asymmetries in H+/K+-ATPase and cell membrane potentials comprise a very early step in left-right patterning, Cell, 111(1): 77-89
PDF

Rutenberg, J., Cheng, S. M., and Levin, M. (2002), Early embryonic expression of ion channels and pumps in chick and Xenopus development, Developmental Dynamics, 225(4): 469-484
PDF

Cheng, S. M., Chen, I., and Levin, M. (2002), Katp channel activity is required for hatching in Xenopus embryos, Developmental Dynamics, 225(4): 588-591
PDF

Levin, M. (2002), Isolation and community: A review of the role of gap-junctional communication in embryonic patterning, Journal of Membrane Biology, 185(3): 177-192
PDF

2001

< Back to Years

Mercola, M., and Levin, M. (2001), Left-Right asymmetry determination in vertebrates, Annual Review of Cell and Developmental Biology, 17: 779-805
PDF

Levin, M. (2001), Asymmetry of Body and Brain: Embryological and Twin Studies, in N. Smelser and P. Baltes (Eds.), International Encyclopedia of the Social and Behavioral Sciences, Elsevier: Oxford, UK, pp. 853-859
PDF

2000

< Back to Years

Levin, M., and Mercola, M. (2000), Expression of connexin 30 in Xenopus embryos and its involvement in hatching gland function, Developmental Dynamics, 219(1): 96-101
PDF

1999

< Back to Years

Levin, M. (1999), Matrix-based GA representations in a model of evolving animal communication, in L. Chambers (Ed.), The Practical Handbook of Genetic Algorithms: Complex Coding Systems, Vol. 3, ch.5, pp. 103-117, CRC Press: Boca Raton, FL

Levin, M. (1999), Twinning and embryonic left-right asymmetry, Laterality, 4(3): 197-208
PDF

Zhu, L., Marvin, M. J., Gardiner, A., Lassar, A. B., Mercola, M., Stern, C. D., and Levin, M. (1999), Cerberus regulates left-right asymmetry of the embryonic head and heart, Current Biology, 9(17): 931-938
PDF

Levin, M., and Mercola, M. (1999), Gap Junction-Mediated Transfer of Left-Right Patterning Signals in the Early Chick Blastoderm is Upstream of Shh Asymmetry in the Node, Development, 126(21): 4703-4714
PDF

Levin, M. (1999), Left-right asymmetry in animal embryogenesis, in G. Palyi, C. Zucchi, and L. Caglioti (Eds.), Advances in Biochirality, ch. 12, pp. 137-152, Elsevier Science LTD: Oxford, UK
PDF

Levin, M. (1999), Endogenous electromagnetic fields and radiations in regeneration, development, and neoplasm, Proceedings of the First World Congress on the Effects of Electricity and Magnetism in the Natural World, Madeira, Portugal

1998

< Back to Years

Levin, M. (1998), The roles of activin and follistatin signaling in chick gastrulation, International Journal of Developmental Biology, 42(4): 553-559
PDF | Figures

Levin, M., and Mercola, M. (1998), Gap junctions are involved in the early generation of left right asymmetry, Developmental Biology, 203(1): 90-105
PDF

Levin, M., and Mercola, M. (1998), Evolutionary conservation of mechanisms upstream of asymmetric nodal expression: Reconciling chick and Xenopus, Developmental Genetics, 23(3): 185-193
PDF

Levin, M. (1998), Left-Right asymmetry and the chick embryo, Seminars in Cell & Developmental Biology, 9(1): 67-76
PDF

Levin, M., and Mercola, M. (1998), The compulsion of chirality: toward an understanding of left-right asymmetry, Genes & Development, 12(6): 763-769
PDF

1997

< Back to Years

Levin, M., and Ernst, S. G. (1997), Applied DC magnetic fields cause alterations in the time of cell divisions and developmental abnormalities in early sea urchin embryos, Bioelectromagnetics, 18(3): 255-263
PDF

Levin, M., Pagan, S., Roberts, D. J., Cooke, J., Kuehn, M. R., and Tabin, C. J. (1997), Left/Right Patterning Signals and the Independent Regulation of Different Aspects of Situs in the Chick Embryo, Developmental Biology, 189(1): 57-67
PDF

Levin, M., and Nascone, N. (1997), Two molecular models of initial left-right asymmetry generation, Medical Hypotheses, 49(5): 429-435
PDF

Levin, M. (1997), Left-right asymmetry in vertebrate embryogenesis, BioEssays, 19(4): 287-296 [cover]
PDF | Link

1996

< Back to Years

Levin, M., Roberts, D. J., Holmes, L. B., and Tabin, C. (1996), Laterality defects in conjoined twins, Nature, 384(6607): 321
PDF

1995

< Back to Years

Levin, M., and Ernst, S. G. (1995), Applied AC and DC Magnetic Fields Cause Alterations in the Mitotic Cycle of Early Sea Urchin Embryos, Bioelectromagnetics, 16(4): 231-240
PDF

Levin, M., Johnson, R. L., Stern, C. D., Kuehn, M., and Tabin, C. (1995), A molecular pathway determining left-right asymmetry in chick embryogenesis, Cell, 82(5): 803-814 [cover]
PDF

Levin, M. (1995), Use of Genetic Algorithms to Solve Biomedical Problems, M.D. Computing, 12(3): 193-198
PDF

Levin, M. (1995), The evolution of understanding: A genetic algorithm model of the evolution of animal communication, BioSystems, 36(3): 167-178
PDF

Levin, M. (1995), Locating putative protein signal sequences, in L. Chambers (Ed.), The Practical Handbook of Genetic Algorithms: New Frontiers, Vol. 2, ch. 2, pp. 53-66, CRC Press: Boca Raton, FL
PDF

1994

< Back to Years

Levin, M. (1994), A Julia set model of field-directed morphogenesis: developmental biology and artificial life, Computer Applications in the Biosciences, 10(2): 85-103
PDF

Levin, M., (1994), Discontinuous and alternate q-system fractals, Computers and Graphics, 18(6): 873-884
PDF

1993

< Back to Years

Levin, M. (1993), Current and potential applications of bioelectromagnetics in medicine, Subtle Energies & Energy Medicine Journal, 4(1): 77-87
PDF

Conferences, Abstracts, and Poster Sessions

< Back to Years

Etcheverry, M., Levin, M., Moulin-Frier, C., and Oudeyer, P.-Y. (2023), SBMLtoODEjax: Efficient Simulation and Optimization of Biological Network Models in JAX, NeurIPS 2023 AI for Science Workshop, New Orleans, LA
Murugan, N., Vigran, H., Miller, K., Pham, Q., Golding, A., Kane, A., Kaplan, D., and Levin, M. (2021), Brief multi-drug treatment via a wearable silk-hydrogel bioreactor induces long-term limb re-patterning and regeneration in adult Xenopus Laevis, The FASEB Journal, 35(S1), doi:10.1096/fasebj.2021.35.s1.03874
Novak, R., Choe, Y., Dinis, A., Ingram, M., Keshari, V., Nestor, B. A., Super, M., Levin, M., and Ingber, D. E. (2020), Xenopticon: Microfluidic platform for time-resolved analysis of Xenopus embryo development, Proceedings of 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2017), 1639-1640
Blackiston, D., Adams, D., Lemire, J., and Levin, M. (2010), Transmembrane voltage gradient in GlyR-expressing niche cells controls behavior of neural crest derivatives in vivo, Developmental Biology, 344(1): 526
Oviedo, N. J., Morokuma, J., Walentek, P., Kema, I. P., Gu, M. B., Ahn, J.M., Hwang, J. S., Gojobori, T., and Levin, M. (2010), Long-range neural and gap junction protein-mediated cues control polarity during planarian regeneration, Developmental Biology, 344(1): 522
Tseng, A. S., Beane, W. S., Lemire, J. M., Masi, A., and Levin, M. (2010), NaV-mediated sodium transport is required for vertebrate appendage regeneration, Developmental Biology, 344(1): 519
Beane W. S., Morokuma J., and Levin M. (2010), H,K-ATPase-mediated ion transport regulates anterior patterning in regenerating planaria, Developmental Biology, 344(1): 522
Vandenberg, L., and Levin, M. (2010), The Par6 complex is required for both early and late orientation of the left-right axis in Xenopus, Developmental Biology, 344(1): 426-427
Beane, W. S., Oviedo, N.J., Adams, D. S., and Levin, M. (2009), H,K-ATPase-mediated ion transport regulates anterior patterning in regenerating planaria, Mechanisms of Development, 126(S1): S294-S295
Morokuma, J., and Levin, M. (2006), Role of KvLQT-1/minK K+ channel in early embryonic patterning, Developmental Biology, 295(1): 451-
Blum, M., Schweickert, A., Beyer, T., Weber, T., Andre, P., Fischer, A., Viebahn, C., and Levin, M. (2006), A leftward fluid flow precedes nodal induction in Xenopus, Developmental Biology, 295(1): 443
Adams, D. S., Masi, A., and Levin, M. (2006), Xenopus tadpole tail regeneration requires the activity of the proton pump V- ATPase, and proton pumping is sufficient to partially rescue the loss of function phenotype, Developmental Biology, 295(1): 355-356
Levin, M., Adams, D. S., Aw, S., Morokuma, J., and Oviedo, N. J. (2006), Bioelectrical controls of morphogenesis, Developmental Biology, 295(1):331-332
Chen, I., and Levin, M. (2004), The Role of KATP Channels in Development of Left-Right Asymmetry in Xenopus, Journal of Dental Research, 83: A1340
Nogi, T. and Levin, M. (2003), Electrical Controls of Regeneration in Planaria, Developmental Biology, 259: 586
Levin, M. (2003), Electric Embryos: Endogenous Ion Fluxes and Voltage Gradients in Left—Right Asymmetry, Developmental Biology, 259: 482
Adams, D., and Levin, M. (2003), Elements of Left—Right Patterning: Gap Junctions, pH, and Membrane Voltage, Developmental Biology, 259: 482
Fukumoto, T., and Levin, M. (2003), Serotonin Is a Novel Very Early Signaling Mechanism in Left—Right Asymmetry, Developmental Biology, 259: 490
Levin, M., and Mercola, M. (1999), Gap junction-mediated transfer of left-right patterning signals, Molecular Biology of the Cell, 39: 1
Pagan S. M., Levin M., and Tabin C. (1997),From left-right asymmetric gene expression to its morphological manifestations, Journal of Morphology, 232(3): 306
Levin, M., Gonzalez, J. L., and Ernst, S. G. (1991), DC and AC magnetic field effects on early sea-urchin development, Biological Bulletin, 181: 511-